An adolescent with depression treated with sertraline developed cholestasis and bile duct paucity, which resolved with medication discontinuation. Vanishing bile duct syndrome is an acquired destruction of interlobular bile ducts. This type of drug-induced liver injury has been associated with other medications and requires practitioners' awareness of potential hepatotoxicity.
- Dili Drug-induced liver injury
- SSRI Selective serotonin reuptake inhibitor
- VBDS Vanishing bile duct syndrome
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health