Seroprevalence of antibodies against Taenia solium cysticerci among refugees resettled in United States

Seth O'Neal, John Townes, Patricia P. Wilkins, John C. Noh, Deborah Lee, Silvia Rodriguez, Hector H. Garcia, William M. Stauffer

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Neurocysticercosis (NCC) is a disease caused by central nervous system infection by the larval stage of the pork tapeworm, Taenia solium. In developing countries, NCC is a leading cause of adult-onset epilepsy. Case reports of NCC are increasing among refugees resettled to the United States and other nations, but the underlying prevalence among refugee groups is unknown. We tested stored serum samples from the Centers for Disease Control and Prevention Migrant Serum Bank for antibodies against T. solium cysts by using the enzymelinked immunoelectrotransfer blot. Seroprevalence was high among all 4 populations tested: refugees from Burma (23.2%), Lao People's Democratic Republic (18.3%), Bhutan (22.8%), and Burundi (25.8%). Clinicians caring for refugee populations should suspect NCC in patients with seizure, chronic headache, or unexplained neurologic manifestations. Improved understanding of the prevalence of epilepsy and other associated diseases among refugees could guide recommendations for their evaluation and treatment before, during, and after resettlement.

Original languageEnglish (US)
Pages (from-to)431-438
Number of pages8
JournalEmerging Infectious Diseases
Volume18
Issue number3
DOIs
StatePublished - Mar 2012

Fingerprint

Taenia solium
Cysticercus
Refugees
Seroepidemiologic Studies
Neurocysticercosis
Antibodies
Epilepsy
Bhutan
Burundi
Laos
Myanmar
Central Nervous System Infections
Headache Disorders
Centers for Disease Control and Prevention (U.S.)
Neurologic Manifestations
Serum
Population
Developing Countries
Cysts
Seizures

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases
  • Epidemiology

Cite this

Seroprevalence of antibodies against Taenia solium cysticerci among refugees resettled in United States. / O'Neal, Seth; Townes, John; Wilkins, Patricia P.; Noh, John C.; Lee, Deborah; Rodriguez, Silvia; Garcia, Hector H.; Stauffer, William M.

In: Emerging Infectious Diseases, Vol. 18, No. 3, 03.2012, p. 431-438.

Research output: Contribution to journalArticle

O'Neal, Seth ; Townes, John ; Wilkins, Patricia P. ; Noh, John C. ; Lee, Deborah ; Rodriguez, Silvia ; Garcia, Hector H. ; Stauffer, William M. / Seroprevalence of antibodies against Taenia solium cysticerci among refugees resettled in United States. In: Emerging Infectious Diseases. 2012 ; Vol. 18, No. 3. pp. 431-438.
@article{4ea4c43607174e50ab7f144b1d0a91aa,
title = "Seroprevalence of antibodies against Taenia solium cysticerci among refugees resettled in United States",
abstract = "Neurocysticercosis (NCC) is a disease caused by central nervous system infection by the larval stage of the pork tapeworm, Taenia solium. In developing countries, NCC is a leading cause of adult-onset epilepsy. Case reports of NCC are increasing among refugees resettled to the United States and other nations, but the underlying prevalence among refugee groups is unknown. We tested stored serum samples from the Centers for Disease Control and Prevention Migrant Serum Bank for antibodies against T. solium cysts by using the enzymelinked immunoelectrotransfer blot. Seroprevalence was high among all 4 populations tested: refugees from Burma (23.2{\%}), Lao People's Democratic Republic (18.3{\%}), Bhutan (22.8{\%}), and Burundi (25.8{\%}). Clinicians caring for refugee populations should suspect NCC in patients with seizure, chronic headache, or unexplained neurologic manifestations. Improved understanding of the prevalence of epilepsy and other associated diseases among refugees could guide recommendations for their evaluation and treatment before, during, and after resettlement.",
author = "Seth O'Neal and John Townes and Wilkins, {Patricia P.} and Noh, {John C.} and Deborah Lee and Silvia Rodriguez and Garcia, {Hector H.} and Stauffer, {William M.}",
year = "2012",
month = "3",
doi = "10.3201/eid1803.111367",
language = "English (US)",
volume = "18",
pages = "431--438",
journal = "Emerging Infectious Diseases",
issn = "1080-6040",
publisher = "Centers for Disease Control and Prevention (CDC)",
number = "3",

}

TY - JOUR

T1 - Seroprevalence of antibodies against Taenia solium cysticerci among refugees resettled in United States

AU - O'Neal, Seth

AU - Townes, John

AU - Wilkins, Patricia P.

AU - Noh, John C.

AU - Lee, Deborah

AU - Rodriguez, Silvia

AU - Garcia, Hector H.

AU - Stauffer, William M.

PY - 2012/3

Y1 - 2012/3

N2 - Neurocysticercosis (NCC) is a disease caused by central nervous system infection by the larval stage of the pork tapeworm, Taenia solium. In developing countries, NCC is a leading cause of adult-onset epilepsy. Case reports of NCC are increasing among refugees resettled to the United States and other nations, but the underlying prevalence among refugee groups is unknown. We tested stored serum samples from the Centers for Disease Control and Prevention Migrant Serum Bank for antibodies against T. solium cysts by using the enzymelinked immunoelectrotransfer blot. Seroprevalence was high among all 4 populations tested: refugees from Burma (23.2%), Lao People's Democratic Republic (18.3%), Bhutan (22.8%), and Burundi (25.8%). Clinicians caring for refugee populations should suspect NCC in patients with seizure, chronic headache, or unexplained neurologic manifestations. Improved understanding of the prevalence of epilepsy and other associated diseases among refugees could guide recommendations for their evaluation and treatment before, during, and after resettlement.

AB - Neurocysticercosis (NCC) is a disease caused by central nervous system infection by the larval stage of the pork tapeworm, Taenia solium. In developing countries, NCC is a leading cause of adult-onset epilepsy. Case reports of NCC are increasing among refugees resettled to the United States and other nations, but the underlying prevalence among refugee groups is unknown. We tested stored serum samples from the Centers for Disease Control and Prevention Migrant Serum Bank for antibodies against T. solium cysts by using the enzymelinked immunoelectrotransfer blot. Seroprevalence was high among all 4 populations tested: refugees from Burma (23.2%), Lao People's Democratic Republic (18.3%), Bhutan (22.8%), and Burundi (25.8%). Clinicians caring for refugee populations should suspect NCC in patients with seizure, chronic headache, or unexplained neurologic manifestations. Improved understanding of the prevalence of epilepsy and other associated diseases among refugees could guide recommendations for their evaluation and treatment before, during, and after resettlement.

UR - http://www.scopus.com/inward/record.url?scp=84863229417&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84863229417&partnerID=8YFLogxK

U2 - 10.3201/eid1803.111367

DO - 10.3201/eid1803.111367

M3 - Article

C2 - 22377408

AN - SCOPUS:84863229417

VL - 18

SP - 431

EP - 438

JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

SN - 1080-6040

IS - 3

ER -