Abstract
A mechanical vascular occluder was studied in eight pigs to test its efficacy in arteries of different diameters, stability over time, and safety in placement. The main component is a self-expandable spindle made of tubular stainless steel mesh. Simple steel spindles, double spindles, and Dacron-core spindles were placed in the common carotid artery, main renal artery, renal artery branches, and infrarenal aorta. Follow-up arteriograms were obtained immediately, 30-60 minutes, and (except for aortic spindles) 7 days after deployment. The left common carotid artery was occluded in all pigs, regardless of spindle type. In the main renal artery and its branches, simple steel spindles did not achieve complete occlusion. Double and Dacron-core spindles produced immediate occlusion without recanalization on the 1-week follow-up arteriogram, except for one spindle with an incomplete Dacron core and two spindles that did not completely fill the arterial lumen. Two Dacron-core spindles achieved immediate complete occlusion of the infrarenal aorta. No migration was seen with any spindle.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 95-100 |
| Number of pages | 6 |
| Journal | Radiology |
| Volume | 188 |
| Issue number | 1 |
| State | Published - Jul 1993 |
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Keywords
- Carotid arteries, therapeutic blockade, 1721.1269
- Interventional procedures, experimental, 1721.1269, 961.1269
- Renal arteries, therapeutic blockade, 961.1269
ASJC Scopus subject areas
- Radiological and Ultrasound Technology
Cite this
Self-expandable spindle for transcatheter vascular occlusion : In vivo experiments. Work in progress. / Schmitz-Rode, Thomas; Timmermans, Hans; Uchida, Barry; Kichikawa, Kimihiko; Nishida, Norifumi; Günther, Rolf W.; Rosch, Josef.
In: Radiology, Vol. 188, No. 1, 07.1993, p. 95-100.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Self-expandable spindle for transcatheter vascular occlusion
T2 - In vivo experiments. Work in progress
AU - Schmitz-Rode, Thomas
AU - Timmermans, Hans
AU - Uchida, Barry
AU - Kichikawa, Kimihiko
AU - Nishida, Norifumi
AU - Günther, Rolf W.
AU - Rosch, Josef
PY - 1993/7
Y1 - 1993/7
N2 - A mechanical vascular occluder was studied in eight pigs to test its efficacy in arteries of different diameters, stability over time, and safety in placement. The main component is a self-expandable spindle made of tubular stainless steel mesh. Simple steel spindles, double spindles, and Dacron-core spindles were placed in the common carotid artery, main renal artery, renal artery branches, and infrarenal aorta. Follow-up arteriograms were obtained immediately, 30-60 minutes, and (except for aortic spindles) 7 days after deployment. The left common carotid artery was occluded in all pigs, regardless of spindle type. In the main renal artery and its branches, simple steel spindles did not achieve complete occlusion. Double and Dacron-core spindles produced immediate occlusion without recanalization on the 1-week follow-up arteriogram, except for one spindle with an incomplete Dacron core and two spindles that did not completely fill the arterial lumen. Two Dacron-core spindles achieved immediate complete occlusion of the infrarenal aorta. No migration was seen with any spindle.
AB - A mechanical vascular occluder was studied in eight pigs to test its efficacy in arteries of different diameters, stability over time, and safety in placement. The main component is a self-expandable spindle made of tubular stainless steel mesh. Simple steel spindles, double spindles, and Dacron-core spindles were placed in the common carotid artery, main renal artery, renal artery branches, and infrarenal aorta. Follow-up arteriograms were obtained immediately, 30-60 minutes, and (except for aortic spindles) 7 days after deployment. The left common carotid artery was occluded in all pigs, regardless of spindle type. In the main renal artery and its branches, simple steel spindles did not achieve complete occlusion. Double and Dacron-core spindles produced immediate occlusion without recanalization on the 1-week follow-up arteriogram, except for one spindle with an incomplete Dacron core and two spindles that did not completely fill the arterial lumen. Two Dacron-core spindles achieved immediate complete occlusion of the infrarenal aorta. No migration was seen with any spindle.
KW - Carotid arteries, therapeutic blockade, 1721.1269
KW - Interventional procedures, experimental, 1721.1269, 961.1269
KW - Renal arteries, therapeutic blockade, 961.1269
UR - http://www.scopus.com/inward/record.url?scp=0027325444&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027325444&partnerID=8YFLogxK
M3 - Article
C2 - 8511323
AN - SCOPUS:0027325444
VL - 188
SP - 95
EP - 100
JO - Radiology
JF - Radiology
SN - 0033-8419
IS - 1
ER -