Selenium and Skin Cancer

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Melanoma and the nonmelanoma skin cancers arise from normal cells in the epithelial layer of the skin. Risk factors for skin cancers are complex and involve numerous inherited, environmental, and biological factors including selenoproteins that are involved in the response of the skin to UV-induced oxidative stress. Results from epidemiological studies of dietary, environmental, and supplemental sources of selenium suggest that in some cases selenium reduces, but in other cases increases, the risk for skin cancer in humans. Studies in model systems using compounds that can enter the "central selenium pool", thereby supporting the synthesis of selenoproteins, have also been mixed. It seems likely that there is a U-shaped curve for selenium intake and skin cancer risk, where the risk is highest at both deficient (

Original languageEnglish (US)
Title of host publicationBetaine: Chemistry, Analysis, Function and Effects
PublisherRoyal Society of Chemistry
Pages391-407
Number of pages17
Volume2015-January
Edition9
DOIs
StatePublished - 2015

Publication series

NameFood and Nutritional Components in Focus
Number9
Volume2015-January
ISSN (Print)20451695
ISSN (Electronic)20451709

Fingerprint

Skin Neoplasms
Selenium
selenium
Skin
Selenoproteins
selenoproteins
skin (animal)
Biological Factors
melanoma
epidemiological studies
Epidemiologic Studies
Melanoma
Oxidative Stress
epithelial cells
Oxidative stress
oxidative stress
risk factors
Epithelial Cells
synthesis
skin neoplasms

ASJC Scopus subject areas

  • Food Science
  • Analytical Chemistry

Cite this

Cassidy, P., Leachman, S., & Moos, P. J. (2015). Selenium and Skin Cancer. In Betaine: Chemistry, Analysis, Function and Effects (9 ed., Vol. 2015-January, pp. 391-407). (Food and Nutritional Components in Focus; Vol. 2015-January, No. 9). Royal Society of Chemistry. https://doi.org/10.1039/9781782622215-00391

Selenium and Skin Cancer. / Cassidy, Pamela; Leachman, Sancy; Moos, Philip J.

Betaine: Chemistry, Analysis, Function and Effects. Vol. 2015-January 9. ed. Royal Society of Chemistry, 2015. p. 391-407 (Food and Nutritional Components in Focus; Vol. 2015-January, No. 9).

Research output: Chapter in Book/Report/Conference proceedingChapter

Cassidy, P, Leachman, S & Moos, PJ 2015, Selenium and Skin Cancer. in Betaine: Chemistry, Analysis, Function and Effects. 9 edn, vol. 2015-January, Food and Nutritional Components in Focus, no. 9, vol. 2015-January, Royal Society of Chemistry, pp. 391-407. https://doi.org/10.1039/9781782622215-00391
Cassidy P, Leachman S, Moos PJ. Selenium and Skin Cancer. In Betaine: Chemistry, Analysis, Function and Effects. 9 ed. Vol. 2015-January. Royal Society of Chemistry. 2015. p. 391-407. (Food and Nutritional Components in Focus; 9). https://doi.org/10.1039/9781782622215-00391
Cassidy, Pamela ; Leachman, Sancy ; Moos, Philip J. / Selenium and Skin Cancer. Betaine: Chemistry, Analysis, Function and Effects. Vol. 2015-January 9. ed. Royal Society of Chemistry, 2015. pp. 391-407 (Food and Nutritional Components in Focus; 9).
@inbook{41216e615e68434bbd6070a33d09fa65,
title = "Selenium and Skin Cancer",
abstract = "Melanoma and the nonmelanoma skin cancers arise from normal cells in the epithelial layer of the skin. Risk factors for skin cancers are complex and involve numerous inherited, environmental, and biological factors including selenoproteins that are involved in the response of the skin to UV-induced oxidative stress. Results from epidemiological studies of dietary, environmental, and supplemental sources of selenium suggest that in some cases selenium reduces, but in other cases increases, the risk for skin cancer in humans. Studies in model systems using compounds that can enter the {"}central selenium pool{"}, thereby supporting the synthesis of selenoproteins, have also been mixed. It seems likely that there is a U-shaped curve for selenium intake and skin cancer risk, where the risk is highest at both deficient (",
author = "Pamela Cassidy and Sancy Leachman and Moos, {Philip J.}",
year = "2015",
doi = "10.1039/9781782622215-00391",
language = "English (US)",
volume = "2015-January",
series = "Food and Nutritional Components in Focus",
publisher = "Royal Society of Chemistry",
number = "9",
pages = "391--407",
booktitle = "Betaine: Chemistry, Analysis, Function and Effects",
edition = "9",

}

TY - CHAP

T1 - Selenium and Skin Cancer

AU - Cassidy, Pamela

AU - Leachman, Sancy

AU - Moos, Philip J.

PY - 2015

Y1 - 2015

N2 - Melanoma and the nonmelanoma skin cancers arise from normal cells in the epithelial layer of the skin. Risk factors for skin cancers are complex and involve numerous inherited, environmental, and biological factors including selenoproteins that are involved in the response of the skin to UV-induced oxidative stress. Results from epidemiological studies of dietary, environmental, and supplemental sources of selenium suggest that in some cases selenium reduces, but in other cases increases, the risk for skin cancer in humans. Studies in model systems using compounds that can enter the "central selenium pool", thereby supporting the synthesis of selenoproteins, have also been mixed. It seems likely that there is a U-shaped curve for selenium intake and skin cancer risk, where the risk is highest at both deficient (

AB - Melanoma and the nonmelanoma skin cancers arise from normal cells in the epithelial layer of the skin. Risk factors for skin cancers are complex and involve numerous inherited, environmental, and biological factors including selenoproteins that are involved in the response of the skin to UV-induced oxidative stress. Results from epidemiological studies of dietary, environmental, and supplemental sources of selenium suggest that in some cases selenium reduces, but in other cases increases, the risk for skin cancer in humans. Studies in model systems using compounds that can enter the "central selenium pool", thereby supporting the synthesis of selenoproteins, have also been mixed. It seems likely that there is a U-shaped curve for selenium intake and skin cancer risk, where the risk is highest at both deficient (

UR - http://www.scopus.com/inward/record.url?scp=84951152336&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84951152336&partnerID=8YFLogxK

U2 - 10.1039/9781782622215-00391

DO - 10.1039/9781782622215-00391

M3 - Chapter

AN - SCOPUS:84951152336

VL - 2015-January

T3 - Food and Nutritional Components in Focus

SP - 391

EP - 407

BT - Betaine: Chemistry, Analysis, Function and Effects

PB - Royal Society of Chemistry

ER -