Selective fluorescence labeling of lipids in living cells

Anne B. Neef; Carsten Schultz

doi:10.1002/anie.200805507

Selective fluorescence labeling of lipids in living cells

Anne B. Neef, Carsten Schultz

Research output: Contribution to journal › Article › peer-review

202 Scopus citations

Abstract

Click chemistry in vivo: Three phosphatidic acid derivatives with alkyne groups in their fatty acid chains weresynthesized and incorporated into mammalian cell membranes. Cooper(l) catalyzed and strain-promoted azide-alkyne cycloaddition reactions were used for their visualization (see schematic representation and flourescence microscopic image).-

Original language	English (US)
Pages (from-to)	1498-1500
Number of pages	3
Journal	Angewandte Chemie - International Edition
Volume	48
Issue number	8
DOIs	https://doi.org/10.1002/anie.200805507
State	Published - Feb 9 2009
Externally published	Yes

Keywords

Alkynes
Click chemistry
Fluorescent probes
Phospholipids

ASJC Scopus subject areas

Catalysis
Chemistry(all)

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10.1002/anie.200805507

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abstract = "Click chemistry in vivo: Three phosphatidic acid derivatives with alkyne groups in their fatty acid chains weresynthesized and incorporated into mammalian cell membranes. Cooper(l) catalyzed and strain-promoted azide-alkyne cycloaddition reactions were used for their visualization (see schematic representation and flourescence microscopic image).-",

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KW - Alkynes

KW - Click chemistry

KW - Fluorescent probes

KW - Phospholipids

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Selective fluorescence labeling of lipids in living cells

Abstract

Keywords

ASJC Scopus subject areas

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