Segregation of CD4 and CXCR4 into distinct lipid microdomains in T lymphocytes suggests a mechanism for membrane destabilization by human immunodeficiency virus

Agriculture & Biology

• Human immunodeficiency virus 100%
• Human immunodeficiency virus 1 86%
• T-lymphocytes 64%
• CXCR4 receptor 43%
• lipids 38%
• octoxynol 24%
• virion 22%
• detergents 21%
• chemokine CXCL12 21%
• plasma membrane 18%
• chemokine receptors 18%
• filipin 18%
• cholesterol 18%
• glycosphingolipids 15%
• membrane fusion 15%
• chemokines 15%
• cyclodextrins 15%
• sphingolipids 14%
• cholera toxin 14%
• mononuclear leukocytes 13%
• confocal microscopy 13%
• fluorescence microscopy 12%
• proteins 11%
• fluorescent antibody technique 11%
• cells 11%
• adsorption 10%
• phosphotransferases (kinases) 10%
• glycoproteins 9%
• antibodies 7%
• viruses 7%
• infection 6%

Medicine & Life Sciences

• HIV-1 61%
• HIV 48%
• Lipids 46%
• T-Lymphocytes 43%
• Membranes 42%
• Octoxynol 28%
• Detergents 24%
• Virion 22%
• Lymphocyte Specific Protein Tyrosine Kinase p56(lck) 18%
• Filipin 18%
• Cholesterol 17%
• Cell Membrane 17%
• CXCR4 Receptors 16%
• Cyclodextrins 16%
• Glycosphingolipids 15%
• Virus Internalization 14%
• Membrane Fusion 14%
• Sphingolipids 14%
• Cholera Toxin 13%
• Chemokine Receptors 13%
• Proteins 13%
• Adsorption 12%
• Fluorescence Microscopy 11%
• Confocal Microscopy 11%
• Chemokines 11%
• Protein-Tyrosine Kinases 10%
• Cold Temperature 10%
• Fluorescent Antibody Technique 10%
• Glycoproteins 10%
• Blood Cells 9%
• Signal Transduction 9%
• Viruses 7%
• Antibodies 6%
• Infections 5%