Segmentation of the gallbladder

Effect on bile entry and exit and its clinical relevance in a patient with abdominal pain

Gerbail T. Krishnamurthy, Shakuntala Krishnamurthy, Thomas Milleson, Paul Brown, Donna S. Urstadt

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

BACKGROUND: The effects of folds or septa on gallbladder filling and emptying are not known. METHODS: Gallbladder filling and emptying were measured in seven patients with two chambers (segmental) and compared with 10 subjects with a single chamber (control). Percent bile flow into gallbladder, and percent ejection fraction from the proximal and distal segments, and entire gallbladder were measured with cholecystokinin. RESULTS: Bile entry into gallbladder was similar in both groups. In patients with segmentation, overall emptying was low mostly due to poor emptying of the distal segment. CONCLUSION: Segmentation of the gallbladder does not affect bile entry, but acting as a one-way valve, a fold or septum lowers emptying significantly, mostly from the distal segment.

Original languageEnglish (US)
Pages (from-to)109-115
Number of pages7
JournalNuclear Medicine Communications
Volume28
Issue number2
DOIs
StatePublished - Feb 2007

Fingerprint

Gallbladder
Bile
Abdominal Pain
Gallbladder Emptying
Cholecystokinin

Keywords

  • Cholecystokinin
  • Cholescintigraphy
  • Gallbladder emptying
  • Segmentation
  • Septa

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Segmentation of the gallbladder : Effect on bile entry and exit and its clinical relevance in a patient with abdominal pain. / Krishnamurthy, Gerbail T.; Krishnamurthy, Shakuntala; Milleson, Thomas; Brown, Paul; Urstadt, Donna S.

In: Nuclear Medicine Communications, Vol. 28, No. 2, 02.2007, p. 109-115.

Research output: Contribution to journalArticle

Krishnamurthy, Gerbail T. ; Krishnamurthy, Shakuntala ; Milleson, Thomas ; Brown, Paul ; Urstadt, Donna S. / Segmentation of the gallbladder : Effect on bile entry and exit and its clinical relevance in a patient with abdominal pain. In: Nuclear Medicine Communications. 2007 ; Vol. 28, No. 2. pp. 109-115.
@article{7b32e69011704f3da4a71f198e766a01,
title = "Segmentation of the gallbladder: Effect on bile entry and exit and its clinical relevance in a patient with abdominal pain",
abstract = "BACKGROUND: The effects of folds or septa on gallbladder filling and emptying are not known. METHODS: Gallbladder filling and emptying were measured in seven patients with two chambers (segmental) and compared with 10 subjects with a single chamber (control). Percent bile flow into gallbladder, and percent ejection fraction from the proximal and distal segments, and entire gallbladder were measured with cholecystokinin. RESULTS: Bile entry into gallbladder was similar in both groups. In patients with segmentation, overall emptying was low mostly due to poor emptying of the distal segment. CONCLUSION: Segmentation of the gallbladder does not affect bile entry, but acting as a one-way valve, a fold or septum lowers emptying significantly, mostly from the distal segment.",
keywords = "Cholecystokinin, Cholescintigraphy, Gallbladder emptying, Segmentation, Septa",
author = "Krishnamurthy, {Gerbail T.} and Shakuntala Krishnamurthy and Thomas Milleson and Paul Brown and Urstadt, {Donna S.}",
year = "2007",
month = "2",
doi = "10.1097/MNM.0b013e328013eb2f",
language = "English (US)",
volume = "28",
pages = "109--115",
journal = "Nuclear Medicine Communications",
issn = "0143-3636",
publisher = "Lippincott Williams and Wilkins",
number = "2",

}

TY - JOUR

T1 - Segmentation of the gallbladder

T2 - Effect on bile entry and exit and its clinical relevance in a patient with abdominal pain

AU - Krishnamurthy, Gerbail T.

AU - Krishnamurthy, Shakuntala

AU - Milleson, Thomas

AU - Brown, Paul

AU - Urstadt, Donna S.

PY - 2007/2

Y1 - 2007/2

N2 - BACKGROUND: The effects of folds or septa on gallbladder filling and emptying are not known. METHODS: Gallbladder filling and emptying were measured in seven patients with two chambers (segmental) and compared with 10 subjects with a single chamber (control). Percent bile flow into gallbladder, and percent ejection fraction from the proximal and distal segments, and entire gallbladder were measured with cholecystokinin. RESULTS: Bile entry into gallbladder was similar in both groups. In patients with segmentation, overall emptying was low mostly due to poor emptying of the distal segment. CONCLUSION: Segmentation of the gallbladder does not affect bile entry, but acting as a one-way valve, a fold or septum lowers emptying significantly, mostly from the distal segment.

AB - BACKGROUND: The effects of folds or septa on gallbladder filling and emptying are not known. METHODS: Gallbladder filling and emptying were measured in seven patients with two chambers (segmental) and compared with 10 subjects with a single chamber (control). Percent bile flow into gallbladder, and percent ejection fraction from the proximal and distal segments, and entire gallbladder were measured with cholecystokinin. RESULTS: Bile entry into gallbladder was similar in both groups. In patients with segmentation, overall emptying was low mostly due to poor emptying of the distal segment. CONCLUSION: Segmentation of the gallbladder does not affect bile entry, but acting as a one-way valve, a fold or septum lowers emptying significantly, mostly from the distal segment.

KW - Cholecystokinin

KW - Cholescintigraphy

KW - Gallbladder emptying

KW - Segmentation

KW - Septa

UR - http://www.scopus.com/inward/record.url?scp=33846005842&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846005842&partnerID=8YFLogxK

U2 - 10.1097/MNM.0b013e328013eb2f

DO - 10.1097/MNM.0b013e328013eb2f

M3 - Article

VL - 28

SP - 109

EP - 115

JO - Nuclear Medicine Communications

JF - Nuclear Medicine Communications

SN - 0143-3636

IS - 2

ER -