Segmental motion adjacent to an instrumented lumbar fusion: The effect of extension of fusion to the sacrum

Christopher Untch, Qi Liu, Robert Hart

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Study Design. We present an in vitro biomechanical comparison of adjacent segment motion at the cranial segment (L3-L4) for an L4-L5 versus an L4-S1 fusion model using cadaveric lumbosacral spines. Objectives. The purpose is to determine the biomechanical effect on the unfused cranial segment of extending a short lumbar fusion to the sacrum versus stopping at L5. Summary of Background Data. Radiographic evidence of adjacent segment degeneration can occur as a late sequela in patients following lumbar and lumbosacral spinal fusions. It is believed that altered biomechanics adjacent to the fusion construct contribute to these degenerative changes. Little is known regarding changes in cranial adjacent segment mechanics resulting from inclusion of the sacrum compared to ending a fusion at L5. Methods. Seven human cadaveric lumbosacral spines were instrumented with pedicle screws at L4, L5, and S1. Rods were placed from L4-L5 and from L4-S1 to simulate the corresponding fusion models. A material testing system was used to apply load-controlled moments to the spines in flexion-extension, lateral bending, and axial rotation. Electromagnetic sensors were used to record 6 df motion across the L3-L4, L4-L5, and L5-S1 motion segments. Angular displacements were recorded and system stiffness was calculated for each spine and construct. A paired sample t test was used to determine significance of recorded differences. Results. Under flexion-extension loading, the angular displacement in the sagittal plane at L3-L4 for the L4-S1 model was 9.0° compared to 7.8° for the L4-L5 model (+15%; P = 0.002). Under lateral bending loading, L3-L4 motion in the coronal plane for the L4-S1 model was 12.8° and was 14.5° for the L4-L5 model (-12%; P = 0.002). In axial rotation testing, L3-L4 torsional motion for the L4-S1 model was equivalent to the L4-L5 model. Overall system stiffness increased for the L4-S1 model compared with the L4-L5 model. Conclusions. In this load-controlled model, extending fusion across L5-S1 did not consistently increase motion at L3-L4. While it may be difficult to translate this finding to a clinical setting, avoiding fusion to the sacrum in a lower lumbar fusion may not provide significant benefit from the standpoint of avoiding adjacent segment disease.

Original languageEnglish (US)
Pages (from-to)2376-2381
Number of pages6
JournalSpine
Volume29
Issue number21
DOIs
StatePublished - Nov 1 2004

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Sacrum
Spine
Materials Testing
Spinal Fusion
Electromagnetic Phenomena
Mechanics
Biomechanical Phenomena

Keywords

  • Adjacent segment degeneration
  • Biomechanics
  • Fusion
  • Lumbar
  • Lumbosacral

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Orthopedics and Sports Medicine

Cite this

Segmental motion adjacent to an instrumented lumbar fusion : The effect of extension of fusion to the sacrum. / Untch, Christopher; Liu, Qi; Hart, Robert.

In: Spine, Vol. 29, No. 21, 01.11.2004, p. 2376-2381.

Research output: Contribution to journalArticle

Untch, Christopher ; Liu, Qi ; Hart, Robert. / Segmental motion adjacent to an instrumented lumbar fusion : The effect of extension of fusion to the sacrum. In: Spine. 2004 ; Vol. 29, No. 21. pp. 2376-2381.
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N2 - Study Design. We present an in vitro biomechanical comparison of adjacent segment motion at the cranial segment (L3-L4) for an L4-L5 versus an L4-S1 fusion model using cadaveric lumbosacral spines. Objectives. The purpose is to determine the biomechanical effect on the unfused cranial segment of extending a short lumbar fusion to the sacrum versus stopping at L5. Summary of Background Data. Radiographic evidence of adjacent segment degeneration can occur as a late sequela in patients following lumbar and lumbosacral spinal fusions. It is believed that altered biomechanics adjacent to the fusion construct contribute to these degenerative changes. Little is known regarding changes in cranial adjacent segment mechanics resulting from inclusion of the sacrum compared to ending a fusion at L5. Methods. Seven human cadaveric lumbosacral spines were instrumented with pedicle screws at L4, L5, and S1. Rods were placed from L4-L5 and from L4-S1 to simulate the corresponding fusion models. A material testing system was used to apply load-controlled moments to the spines in flexion-extension, lateral bending, and axial rotation. Electromagnetic sensors were used to record 6 df motion across the L3-L4, L4-L5, and L5-S1 motion segments. Angular displacements were recorded and system stiffness was calculated for each spine and construct. A paired sample t test was used to determine significance of recorded differences. Results. Under flexion-extension loading, the angular displacement in the sagittal plane at L3-L4 for the L4-S1 model was 9.0° compared to 7.8° for the L4-L5 model (+15%; P = 0.002). Under lateral bending loading, L3-L4 motion in the coronal plane for the L4-S1 model was 12.8° and was 14.5° for the L4-L5 model (-12%; P = 0.002). In axial rotation testing, L3-L4 torsional motion for the L4-S1 model was equivalent to the L4-L5 model. Overall system stiffness increased for the L4-S1 model compared with the L4-L5 model. Conclusions. In this load-controlled model, extending fusion across L5-S1 did not consistently increase motion at L3-L4. While it may be difficult to translate this finding to a clinical setting, avoiding fusion to the sacrum in a lower lumbar fusion may not provide significant benefit from the standpoint of avoiding adjacent segment disease.

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