Sedentary behavior and cardiovascular morbidity and mortality: A science advisory from the American Heart Association

Deborah Rohm Young, Marie France Hivert, Sofiya Alhassan, Sarah M. Camhi, Jane F. Ferguson, Peter T. Katzmarzyk, Cora E. Lewis, Neville Owen, Cynthia K. Perry, Juned Siddique, Celina M. Yong

Research output: Contribution to journalArticlepeer-review

373 Scopus citations


Epidemiological evidence is accumulating that indicates greater time spent in sedentary behavior is associated with all-cause and cardiovascular morbidity and mortality in adults such that some countries have disseminated broad guidelines that recommend minimizing sedentary behaviors. Research examining the possible deleterious consequences of excess sedentary behavior is rapidly evolving, with the epidemiology-based literature ahead of potential biological mechanisms that might explain the observed associations. This American Heart Association science advisory reviews the current evidence on sedentary behavior in terms of assessment methods, population prevalence, determinants, associations with cardiovascular disease incidence and mortality, potential underlying mechanisms, and interventions. Recommendations for future research on this emerging cardiovascular health topic are included. Further evidence is required to better inform public health interventions and future quantitative guidelines on sedentary behavior and cardiovascular health outcomes.

Original languageEnglish (US)
Pages (from-to)e262-e279
Issue number13
StatePublished - Sep 27 2016


  • AHA Scientific Statements
  • adults
  • cardiovascular disease
  • diabetes mellitus
  • metabolic syndrome
  • mortality
  • prevalence
  • sedentary lifestyle

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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