Screening for Vitamin D Deficiency in Adults: US Preventive Services Task Force Recommendation Statement

Alex H. Krist, Karina W. Davidson, Carol M. Mangione, Michael Cabana, Aaron B. Caughey, Esa M. Davis, Katrina E. Donahue, Chyke A. Doubeni, John W. Epling, Martha Kubik, Li Li, Gbenga Ogedegbe, Douglas K. Owens, Lori Pbert, Michael Silverstein, James Stevermer, Chien Wen Tseng, John B. Wong

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations

Abstract

Importance: Vitamin D is a fat-soluble vitamin that performs an important role in calcium homeostasis and bone metabolism and also affects many other cellular regulatory functions outside the skeletal system. Vitamin D requirements may vary by individual; thus, no one serum vitamin D level cutpoint defines deficiency, and no consensus exists regarding the precise serum levels of vitamin D that represent optimal health or sufficiency. Objective: To update its 2014 recommendation, the US Preventive Services Task Force (USPSTF) commissioned a systematic review on screening for vitamin D deficiency, including the benefits and harms of screening and early treatment. Population: Community-dwelling, nonpregnant adults who have no signs or symptoms of vitamin D deficiency or conditions for which vitamin D treatment is recommended. Evidence Assessment: The USPSTF concludes that the overall evidence on the benefits of screening for vitamin D deficiency is lacking. Therefore, the balance of benefits and harms of screening for vitamin D deficiency in asymptomatic adults cannot be determined. Recommendation: The USPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms of screening for vitamin D deficiency in asymptomatic adults. (I statement).

Original languageEnglish (US)
Pages (from-to)1436-1442
Number of pages7
JournalJAMA - Journal of the American Medical Association
Volume325
Issue number14
DOIs
StatePublished - Apr 13 2021

ASJC Scopus subject areas

  • Medicine(all)

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