Abstract
We report positivity rates of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infection at each anatomic site among asymptomatic men who have sex with men (MSM). We calculated the number needed to screen (NNS) to detect CT and NG infection at each anatomic site. From 2006 to 2010, we enrolled Thai MSM, age ≥ 18 years into the Bangkok MSM Cohort Study. Participants underwent physical examination and had rectal, urethral, and pharyngeal screening for CT and NG infection using nucleic acid amplification tests (NAATs). Of 1744 enrollees, 1696 (97.2%) had no symptoms of CT and NG infection. The positivity rates of CT and NG infection at any site were 14.3% (rectum, urethra, pharynx) and 6.4% (rectum, urethra), respectively. The NNS to detect rectal CT and rectal NG infections was 10 and 16, respectively (p < 0.05). For urethral infection, the NNS of CT was lower than the NNS of NG (22, 121: p < 0.05). The lowest NNS found for rectal CT infection was in HIV-infected MSM (6, 5–8). Asymptomatic CT and NG infection were common among MSM in Bangkok, Thailand and frequently detected in the rectum. In setting where screening in all specimens using NAAT is not feasible, rectal screening should be a priority.
| Original language | English (US) |
|---|---|
| Journal | International Journal of STD and AIDS |
| DOIs | |
| State | Accepted/In press - Jan 1 2017 |
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Keywords
- Chlamydia trachomatis
- Neisseria gonorrhoeae
- Men who have sex with men
- screening
ASJC Scopus subject areas
- Dermatology
- Public Health, Environmental and Occupational Health
- Pharmacology (medical)
- Infectious Diseases
Cite this
Screening for Chlamydia trachomatis and Neisseria gonorrhoeae infection among asymptomatic men who have sex with men in Bangkok, Thailand. / Pattanasin, Sarika; Dunne, Eileen F.; Wasinrapee, Punneeporn; Tongtoyai, Jaray; Chonwattana, Wannee; Sriporn, Anuwat; Luechai, Pikunchai; Mock, Philip A.; Chitwarakorn, Anupong; Holtz, Timothy H.; Curlin, Marcel.
In: International Journal of STD and AIDS, 01.01.2017.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Screening for Chlamydia trachomatis and Neisseria gonorrhoeae infection among asymptomatic men who have sex with men in Bangkok, Thailand
AU - Pattanasin, Sarika
AU - Dunne, Eileen F.
AU - Wasinrapee, Punneeporn
AU - Tongtoyai, Jaray
AU - Chonwattana, Wannee
AU - Sriporn, Anuwat
AU - Luechai, Pikunchai
AU - Mock, Philip A.
AU - Chitwarakorn, Anupong
AU - Holtz, Timothy H.
AU - Curlin, Marcel
PY - 2017/1/1
Y1 - 2017/1/1
N2 - We report positivity rates of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infection at each anatomic site among asymptomatic men who have sex with men (MSM). We calculated the number needed to screen (NNS) to detect CT and NG infection at each anatomic site. From 2006 to 2010, we enrolled Thai MSM, age ≥ 18 years into the Bangkok MSM Cohort Study. Participants underwent physical examination and had rectal, urethral, and pharyngeal screening for CT and NG infection using nucleic acid amplification tests (NAATs). Of 1744 enrollees, 1696 (97.2%) had no symptoms of CT and NG infection. The positivity rates of CT and NG infection at any site were 14.3% (rectum, urethra, pharynx) and 6.4% (rectum, urethra), respectively. The NNS to detect rectal CT and rectal NG infections was 10 and 16, respectively (p < 0.05). For urethral infection, the NNS of CT was lower than the NNS of NG (22, 121: p < 0.05). The lowest NNS found for rectal CT infection was in HIV-infected MSM (6, 5–8). Asymptomatic CT and NG infection were common among MSM in Bangkok, Thailand and frequently detected in the rectum. In setting where screening in all specimens using NAAT is not feasible, rectal screening should be a priority.
AB - We report positivity rates of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infection at each anatomic site among asymptomatic men who have sex with men (MSM). We calculated the number needed to screen (NNS) to detect CT and NG infection at each anatomic site. From 2006 to 2010, we enrolled Thai MSM, age ≥ 18 years into the Bangkok MSM Cohort Study. Participants underwent physical examination and had rectal, urethral, and pharyngeal screening for CT and NG infection using nucleic acid amplification tests (NAATs). Of 1744 enrollees, 1696 (97.2%) had no symptoms of CT and NG infection. The positivity rates of CT and NG infection at any site were 14.3% (rectum, urethra, pharynx) and 6.4% (rectum, urethra), respectively. The NNS to detect rectal CT and rectal NG infections was 10 and 16, respectively (p < 0.05). For urethral infection, the NNS of CT was lower than the NNS of NG (22, 121: p < 0.05). The lowest NNS found for rectal CT infection was in HIV-infected MSM (6, 5–8). Asymptomatic CT and NG infection were common among MSM in Bangkok, Thailand and frequently detected in the rectum. In setting where screening in all specimens using NAAT is not feasible, rectal screening should be a priority.
KW - Chlamydia trachomatis
KW - Neisseria gonorrhoeae
KW - Men who have sex with men
KW - screening
UR - http://www.scopus.com/inward/record.url?scp=85042565369&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85042565369&partnerID=8YFLogxK
U2 - 10.1177/0956462417744904
DO - 10.1177/0956462417744904
M3 - Article
C2 - 29198179
AN - SCOPUS:85042565369
JO - International Journal of STD and AIDS
JF - International Journal of STD and AIDS
SN - 0956-4624
ER -