Scheme for efficient fiber-based CARS probe

Mihaela Balu, Gangjun Liu, Zhongping Chen, Bruce J. Tromberg, Eric O. Potma

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We demonstrate a fiber-based probe for maximum collection of the Coherent anti-Stokes Raman Scattering (CARS) signal in biological tissues. We discuss the design challenges including capturing the back-scattered forward generated CARS signal in the sample and the effects of fiber nonlinearities on the propagating pulses. Three different biological tissues were imaged in vitro in order to assess the performance of our fiberdelivered probe for CARS imaging, a tool which we consider an important advance towards label-free, in vivo probing of superficial tissues.

Original languageEnglish (US)
Title of host publicationMultiphoton Microscopy in the Biomedical Sciences X
DOIs
StatePublished - May 7 2010
EventMultiphoton Microscopy in the Biomedical Sciences X - San Francisco, CA, United States
Duration: Jan 24 2010Jan 26 2010

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7569
ISSN (Print)1605-7422

Other

OtherMultiphoton Microscopy in the Biomedical Sciences X
CountryUnited States
CitySan Francisco, CA
Period1/24/101/26/10

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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    Balu, M., Liu, G., Chen, Z., Tromberg, B. J., & Potma, E. O. (2010). Scheme for efficient fiber-based CARS probe. In Multiphoton Microscopy in the Biomedical Sciences X [75693A] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 7569). https://doi.org/10.1117/12.855187