SCAI expert consensus statement on operator and institutional requirements for PFO closure for secondary prevention of paradoxical embolic stroke: The American Academy of Neurology affirms the value of this statement as an educational tool for neurologists.

Eric Horlick, Clifford J. Kavinsky, Zahid Amin, Konstantinos Dean Boudoulas, John D. Carroll, Ziyad M. Hijazi, Dana Leifer, Helmi Lutsep, John F. Rhodes, Jonathan M. Tobis

Research output: Contribution to journalArticle

4 Scopus citations


Until recently, evidence to support Patent Foramen Ovale (PFO) closure for secondary prevention of recurrent stroke has been controversial. Publication of high-quality evidence from randomized clinical trials and the subsequent FDA approval of two devices for percutaneous PFO closure is expected to increase the volume of PFO closure procedures not only in the United States but worldwide. As this technology is disseminated broadly to the public, ensuring the safe and efficacious performance of PFO closure is essential to mitigate risk and avoid unnecessary procedures. This document, prepared by a multi-disciplinary writing group convened by the Society for Cardiovascular Angiography and Interventions and including representatives from the American Academy of Neurology, makes recommendations for institutional infrastructure and individual skills necessary to initiate and maintain an active PFO/stroke program, with emphasis on shared decision making and patient-centered care.

Original languageEnglish (US)
Pages (from-to)859-874
Number of pages16
JournalCatheterization and Cardiovascular Interventions
Issue number5
StatePublished - Apr 1 2019



  • closure
  • comparative effectiveness/patient centered outcomes research
  • evidence-based medicine
  • structural heart disease intervention

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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