Ruptured mitral chordae tendineae may be a frequent and insignificant complication in the mitral valve prolapse syndrome

E. Grenadier, S. Keidar, David Sahn, G. Alpan, S. J. Goldberg, L. M. Valdez Cruz, C. O. Lima, J. V. Barron, H. D. Allen, A. Palant

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

In this study, we performed 512 echocardiographic studies on 264 consecutive, unselected patients with the idiopathic mitral valve prolapse syndrome. Twenty-eight patients (10.6%) had evidence of ruptured chordae tendineae of the mitral valve on M-mode examination and in 24 the diagnosis was confirmed by two-dimensional echocardiography. Mild to severe mitral insufficiency was proven in all of them by left ventriculography during cardiac catheterization. Eight patients underwent surgery to relieve symptomatic severe mitral regurgitation. At operation all had myxomatous degeneration of the mitral valve, two patients were found to have rupture of anterior mitral chordae, and six had rupture of posterior mitral chordae. Twenty (71%) patients with chordal rupture had either mild symptoms or were completely asymptomatic. It is concluded that chordal rupture in patients with the mitral valve prolapse syndrome may be present in asymptomatic patients and go undetected clinically in a substantial number of patients unless a high index of suspicion is maintained. Serial M-mode and two-dimensional echocardiographic studies are of importance in identifying the progression of prolapse findings and may reveal the natural history of this pathologic condition in asymptomatic patients.

Original languageEnglish (US)
Pages (from-to)1006-1015
Number of pages10
JournalEuropean Heart Journal
Volume6
Issue number12
StatePublished - Dec 1985
Externally publishedYes

Fingerprint

Chordae Tendineae
Mitral Valve Prolapse
Rupture
Complications
Echocardiography
Surgery
Degeneration
Progression
Mitral Valve Insufficiency
Cardiac
Mitral Valve
Consecutive
Asymptomatic Diseases
Prolapse
Cardiac Catheterization

Keywords

  • Chordate tendineac
  • Mitral calcve prolapse

ASJC Scopus subject areas

  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Physiology (medical)
  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Grenadier, E., Keidar, S., Sahn, D., Alpan, G., Goldberg, S. J., Valdez Cruz, L. M., ... Palant, A. (1985). Ruptured mitral chordae tendineae may be a frequent and insignificant complication in the mitral valve prolapse syndrome. European Heart Journal, 6(12), 1006-1015.

Ruptured mitral chordae tendineae may be a frequent and insignificant complication in the mitral valve prolapse syndrome. / Grenadier, E.; Keidar, S.; Sahn, David; Alpan, G.; Goldberg, S. J.; Valdez Cruz, L. M.; Lima, C. O.; Barron, J. V.; Allen, H. D.; Palant, A.

In: European Heart Journal, Vol. 6, No. 12, 12.1985, p. 1006-1015.

Research output: Contribution to journalArticle

Grenadier, E, Keidar, S, Sahn, D, Alpan, G, Goldberg, SJ, Valdez Cruz, LM, Lima, CO, Barron, JV, Allen, HD & Palant, A 1985, 'Ruptured mitral chordae tendineae may be a frequent and insignificant complication in the mitral valve prolapse syndrome', European Heart Journal, vol. 6, no. 12, pp. 1006-1015.
Grenadier E, Keidar S, Sahn D, Alpan G, Goldberg SJ, Valdez Cruz LM et al. Ruptured mitral chordae tendineae may be a frequent and insignificant complication in the mitral valve prolapse syndrome. European Heart Journal. 1985 Dec;6(12):1006-1015.
Grenadier, E. ; Keidar, S. ; Sahn, David ; Alpan, G. ; Goldberg, S. J. ; Valdez Cruz, L. M. ; Lima, C. O. ; Barron, J. V. ; Allen, H. D. ; Palant, A. / Ruptured mitral chordae tendineae may be a frequent and insignificant complication in the mitral valve prolapse syndrome. In: European Heart Journal. 1985 ; Vol. 6, No. 12. pp. 1006-1015.
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