Role of quantitative planar thallium-201 imaging for determining viability in patients with acute myocardial infarction and a totally occluded infarct- related artery

P. J. Sabia, E. R. Powers, M. Ragosta, W. H. Smith, D. D. Watson, S. Kaul

    Research output: Contribution to journalArticle

    21 Scopus citations

    Abstract

    We studied 57 patients with a recent infarction and an occluded infarct- related artery to test the hypothesis that the amount of 201Tl on delayed planar images correlates with the extent of viable myocardium after acute myocardial infarction. There was a significant (p < 0.001) correlation between mean 201Tl activity in the infarct zone and regional wall motion score in that zone both at baseline (r = -0.60, n = 57) and 1 mo after attempted angioplasty (r = -0.67, n = 48), with better function being associated with greater 201Tl uptake in the delayed images. There was no correlation between the number of segments showing redistribution and the wall motion score. We conclude that in patients with recent myocardial infarction and an occluded infarct-related artery, the average 201Tl activity within the infarct zone on delayed planar imaging correlates well with the extent of viable myocardium in that zone. The presence or absence of redistribution does not influence these results.

    Original languageEnglish (US)
    Pages (from-to)728-736
    Number of pages9
    JournalJournal of Nuclear Medicine
    Volume34
    Issue number5
    StatePublished - Jan 1 1993

    ASJC Scopus subject areas

    • Radiology Nuclear Medicine and imaging

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