Role of infiltrated leucocytes in tumour growth and spread

E. Y. Lin; J. W. Pollard

doi:10.1038/sj.bjc.6601705

Role of infiltrated leucocytes in tumour growth and spread

E. Y. Lin, J. W. Pollard

Research output: Contribution to journal › Short survey › peer-review

222 Scopus citations

Abstract

Leucocytes are a major component of the tumour microenvironment. Recent studies have indicated that the infiltration and activity of these host cells are regulated by the tumour to promote its survival and progression. Through the production of an array of growth factors, proteases and angiogenic mediators, leucocytes in the tumour microenvironment promote tumour growth, angiogenesis and metastasis.

Original language	English (US)
Pages (from-to)	2053-2058
Number of pages	6
Journal	British Journal of Cancer
Volume	90
Issue number	11
DOIs	https://doi.org/10.1038/sj.bjc.6601705
State	Published - Jun 1 2004
Externally published	Yes

Keywords

Angiogenesis
Leucocyte
Metastasis
Progression
Tumour

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1038/sj.bjc.6601705

Cite this

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abstract = "Leucocytes are a major component of the tumour microenvironment. Recent studies have indicated that the infiltration and activity of these host cells are regulated by the tumour to promote its survival and progression. Through the production of an array of growth factors, proteases and angiogenic mediators, leucocytes in the tumour microenvironment promote tumour growth, angiogenesis and metastasis.",

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KW - Leucocyte

KW - Metastasis

KW - Progression

KW - Tumour

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Role of infiltrated leucocytes in tumour growth and spread

Abstract

Keywords

ASJC Scopus subject areas

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