Role of infiltrated leucocytes in tumour growth and spread

E. Y. Lin, J. W. Pollard

Research output: Contribution to journalShort survey

182 Scopus citations

Abstract

Leucocytes are a major component of the tumour microenvironment. Recent studies have indicated that the infiltration and activity of these host cells are regulated by the tumour to promote its survival and progression. Through the production of an array of growth factors, proteases and angiogenic mediators, leucocytes in the tumour microenvironment promote tumour growth, angiogenesis and metastasis.

Original languageEnglish (US)
Pages (from-to)2053-2058
Number of pages6
JournalBritish Journal of Cancer
Volume90
Issue number11
DOIs
StatePublished - Jun 1 2004

Keywords

  • Angiogenesis
  • Leucocyte
  • Metastasis
  • Progression
  • Tumour

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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