Role of electron microscopy and other special techniques in the diagnosis of childhood round cell tumors

Gary W. Mierau, Douglas A. Weeks, M. John Hicks

Research output: Contribution to journalEditorialpeer-review

33 Scopus citations

Abstract

A series of case presentations show unique challenges associated with childhood round cell tumors and the role of ancillary techniques in diagnosis. Electron microscopy is shown to be the most powerful individual technique. Immunohistochemistry is legs effective but also essential. Other ancillary techniques may provide needed additional diagnostic information. Because this is an area where it is of great importance to secure the most rapid, accurate, and specific diagnosis possible, an integrated multimodal approach is recommended-incorporating light microscopic, electron microscopic, and immunohistochemical studies as a matter of routine, and providing for cytogenetic and/or molecular diagnostic studies as indicated.

Original languageEnglish (US)
Pages (from-to)1347-1355
Number of pages9
JournalHuman Pathology
Volume29
Issue number12
DOIs
StatePublished - Jan 1 1998

Keywords

  • Childhood
  • Electron microscopy
  • Immunohistochemistry
  • Neoplasia
  • Round cell tumors

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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