Role of CD8+ T lymphocytes in control of Mycobacterium tuberculosis infection

Jeff E. Grotzke, David M. Lewinsohn

Research output: Contribution to journalShort survey

82 Scopus citations

Abstract

Tuberculosis remains a global health concern. Control of infection is dependent on cell-mediated immune responses, with CD4+ T lymphocytes playing a central role. In this article, data supporting the importance of CD8+ T lymphocytes is reviewed, with an emphasis on the unique functional roles that this lymphocyte subset may play.

Original languageEnglish (US)
Pages (from-to)776-788
Number of pages13
JournalMicrobes and Infection
Volume7
Issue number4
DOIs
StatePublished - Apr 2005

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Keywords

  • Antigen presentation
  • CD8-positive T-lymphocytes
  • Immunologic surveillance
  • Tuberculosis

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Infectious Diseases

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