Risk stratification of sudden cardiac death in hypertension

Larisa Tereshchenko, Elsayed Z. Soliman, Barry R. Davis, Suzanne Oparil

    Research output: Contribution to journalArticle

    4 Scopus citations

    Abstract

    In the United States, up to 450,000 people per year die suddenly; an average of 1 sudden death every 70. s. Strategies for preventing sudden cardiac death are urgently needed. Systemic arterial hypertension is a major risk factor for sudden cardiac death and the increasing burden of hypertension is a worldwide problem. The lifetime risk of sudden cardiac death at 30. years of age is higher by 30% in individuals with hypertension. Each 20/10. mm. Hg increase in systolic/diastolic blood pressure, is associated with a 20% additional increase in sudden cardiac death risk. Theoretically, antihypertensive treatment should be an effective strategy for sudden cardiac death prevention. However, a recent meta-analysis of 15 randomized controlled trials showed that antihypertensive treatment does not reduce the incidence of sudden cardiac death. This manuscript reviews ECG predictors of sudden cardiac death and the importance of risk stratification for appropriate management of hypertension.

    Original languageEnglish (US)
    JournalJournal of Electrocardiology
    DOIs
    Publication statusAccepted/In press - 2017

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    Keywords

    • Global electrical heterogeneity
    • Hypertension
    • Sudden cardiac death

    ASJC Scopus subject areas

    • Cardiology and Cardiovascular Medicine

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