Risk of uterine leiomyomata among premenopausal women in relation to body size and cigarette smoking

Lynn Marshall, Donna Spiegelman, JoAnn E. Manson, Marlene B. Goldman, Robert L. Barbieri, Meir J. Stampfer, Walter C. Willett, David J. Hunter

Research output: Contribution to journalArticle

97 Citations (Scopus)

Abstract

To investigate whether factors influencing ovarian function affect risk of uterine leiomyomata, we examined prospectively the association of new diagnoses confirmed by ultrasound or hysterectomy with body mass index, weight change, height, and cigarette smoking among 94,095 premenopausal women with intact uteri, who were ages 25-42 years at the start of follow-up in 1989. We assessed body mass index and cigarette smoking from responses on the study questionnaire completed just before diagnosis. During 322,775 person- years, 2,967 new cases of uterine leiomyomata confirmed by ultrasound or hysterectomy were reported. Risk among all cases confirmed by ultrasound or hysterectomy increased with increasing adult body mass index. The multivariate relative risks (RR) and 95% confidence intervals (CI) according to body mass index categories of

Original languageEnglish (US)
Pages (from-to)511-517
Number of pages7
JournalEpidemiology
Volume9
Issue number5
StatePublished - Sep 1998

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Leiomyoma
Body Size
Body Mass Index
Smoking
Hysterectomy
Uterus
Confidence Intervals
Weights and Measures

Keywords

  • Body mass index
  • Cohort studies
  • Height
  • Leiomyoma
  • Smoking
  • Uterine neoplasms

ASJC Scopus subject areas

  • Epidemiology

Cite this

Marshall, L., Spiegelman, D., Manson, J. E., Goldman, M. B., Barbieri, R. L., Stampfer, M. J., ... Hunter, D. J. (1998). Risk of uterine leiomyomata among premenopausal women in relation to body size and cigarette smoking. Epidemiology, 9(5), 511-517.

Risk of uterine leiomyomata among premenopausal women in relation to body size and cigarette smoking. / Marshall, Lynn; Spiegelman, Donna; Manson, JoAnn E.; Goldman, Marlene B.; Barbieri, Robert L.; Stampfer, Meir J.; Willett, Walter C.; Hunter, David J.

In: Epidemiology, Vol. 9, No. 5, 09.1998, p. 511-517.

Research output: Contribution to journalArticle

Marshall, L, Spiegelman, D, Manson, JE, Goldman, MB, Barbieri, RL, Stampfer, MJ, Willett, WC & Hunter, DJ 1998, 'Risk of uterine leiomyomata among premenopausal women in relation to body size and cigarette smoking', Epidemiology, vol. 9, no. 5, pp. 511-517.
Marshall L, Spiegelman D, Manson JE, Goldman MB, Barbieri RL, Stampfer MJ et al. Risk of uterine leiomyomata among premenopausal women in relation to body size and cigarette smoking. Epidemiology. 1998 Sep;9(5):511-517.
Marshall, Lynn ; Spiegelman, Donna ; Manson, JoAnn E. ; Goldman, Marlene B. ; Barbieri, Robert L. ; Stampfer, Meir J. ; Willett, Walter C. ; Hunter, David J. / Risk of uterine leiomyomata among premenopausal women in relation to body size and cigarette smoking. In: Epidemiology. 1998 ; Vol. 9, No. 5. pp. 511-517.
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