Risk of over-diagnosis of COPD in asymptomatic elderly never-smokers

J. A. Hardie, A (Sonia) Buist, W. M. Vollmer, I. Ellingsen, P. S. Bakke, O. Mørkve

Research output: Contribution to journalArticle

360 Citations (Scopus)

Abstract

The Global Initiative for Chronic Obstructive Lung Disease (GOLD) has defined stage 1 chronic obstructive pulmonary disease (COPD) as forced expiratory volume in one second/forced vital capacity (FEV1/FVC)% 1% predicted of >80%. Stage 2 has been defined as FEV1/FVC 1% pred of 70 yrs in Bergen, Norway. A respiratory questionnaire was mailed to a random sample of 2,871 persons aged >70 yrs. In a random, well-defined subgroup of 208 never-smoker respondents with no current respiratory disease and significant dyspnoea or heart disease/hypertension complicated with dyspnoea, 71 were able to perform an acceptable spirometry. Approximately 35% of these healthy, elderly never-smokers had an FEV1/FVC% of 80 yrs ∼50% would be classified as having COPD and approximately one-third would have an FEV1 of 1 was consistently 70 yrs. The criteria used to define the various stages of chronic obstructive pulmonary disease need to be age-specific.

Original languageEnglish (US)
Pages (from-to)1117-1122
Number of pages6
JournalEuropean Respiratory Journal
Volume20
Issue number5
DOIs
StatePublished - Nov 1 2002
Externally publishedYes

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Chronic Obstructive Pulmonary Disease
Dyspnea
Spirometry
Vital Capacity
Forced Expiratory Volume
Norway
Heart Diseases
Hypertension
Surveys and Questionnaires

Keywords

  • Aged
  • Chronic obstructive pulmonary disease
  • Spirometry

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Hardie, J. A., Buist, A. S., Vollmer, W. M., Ellingsen, I., Bakke, P. S., & Mørkve, O. (2002). Risk of over-diagnosis of COPD in asymptomatic elderly never-smokers. European Respiratory Journal, 20(5), 1117-1122. https://doi.org/10.1183/09031936.02.00023202

Risk of over-diagnosis of COPD in asymptomatic elderly never-smokers. / Hardie, J. A.; Buist, A (Sonia); Vollmer, W. M.; Ellingsen, I.; Bakke, P. S.; Mørkve, O.

In: European Respiratory Journal, Vol. 20, No. 5, 01.11.2002, p. 1117-1122.

Research output: Contribution to journalArticle

Hardie, JA, Buist, AS, Vollmer, WM, Ellingsen, I, Bakke, PS & Mørkve, O 2002, 'Risk of over-diagnosis of COPD in asymptomatic elderly never-smokers', European Respiratory Journal, vol. 20, no. 5, pp. 1117-1122. https://doi.org/10.1183/09031936.02.00023202
Hardie, J. A. ; Buist, A (Sonia) ; Vollmer, W. M. ; Ellingsen, I. ; Bakke, P. S. ; Mørkve, O. / Risk of over-diagnosis of COPD in asymptomatic elderly never-smokers. In: European Respiratory Journal. 2002 ; Vol. 20, No. 5. pp. 1117-1122.
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