TY - JOUR
T1 - Risk-based guidelines
T2 - Redefining management of abnormal cervical cancer screening results
AU - Wiser, Amy
AU - Quinlan, Jeffrey D.
AU - Batur, Pelin
N1 - Publisher Copyright:
© 2021. All Rights Reserved.
PY - 2021
Y1 - 2021
N2 - In making the 2019 guidelines for risk-based management of patients with abnormal cervical cancer screening tests and cancer precursors, the guidelines committee shifted from results-based to risk-based management recommendations, based on the patient's immediate and 5-year risks of grade 3 or higher cervical intraepithelial neoplasia (CIN 3+). The risk is determined by current and prior screening results (human papillomavirus infection, cytology testing) and the clinical history including age. An immediate 4% or higher risk of CIN 3+ was established as the dividing line between higher and lower risks, and the corresponding management recommendations. This article reviews the changes and their evidence base and discusses clinical implications of the revised guidelines.
AB - In making the 2019 guidelines for risk-based management of patients with abnormal cervical cancer screening tests and cancer precursors, the guidelines committee shifted from results-based to risk-based management recommendations, based on the patient's immediate and 5-year risks of grade 3 or higher cervical intraepithelial neoplasia (CIN 3+). The risk is determined by current and prior screening results (human papillomavirus infection, cytology testing) and the clinical history including age. An immediate 4% or higher risk of CIN 3+ was established as the dividing line between higher and lower risks, and the corresponding management recommendations. This article reviews the changes and their evidence base and discusses clinical implications of the revised guidelines.
UR - http://www.scopus.com/inward/record.url?scp=85117879988&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85117879988&partnerID=8YFLogxK
U2 - 10.3949/ccjm.88a.20193
DO - 10.3949/ccjm.88a.20193
M3 - Article
C2 - 34598920
AN - SCOPUS:85117879988
SN - 0891-1150
VL - 88
SP - 556
EP - 560
JO - Cleveland Clinic journal of medicine
JF - Cleveland Clinic journal of medicine
IS - 10
ER -