Abstract
There are insufficient toxicity data on the target material propanal diethyl acetal (CAS # 4744-08-5). Hence, in silico evaluation was conducted to determine read-across analogs for this material. Based on structural similarity, reactivity, metabolism data, physical–chemical properties, and expert judgment, analogs acetal (CAS # 105-57-7) and butane, 1,1'-[methylenebis(oxy)]bis- (CAS # 2568-90-3) were identified as read-across materials with sufficient data for toxicological evaluation of genotoxicity.
Original language | English (US) |
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Article number | 110588 |
Journal | Food and Chemical Toxicology |
Volume | 130 |
DOIs | |
State | Published - Aug 2019 |
Keywords
- Environmental Safety
- Genotoxicity
- Local Respiratory Toxicity
- Phototoxicity/Photoallergenicity
- Repeated Dose, Developmental, and Reproductive Toxicity
- Skin Sensitization
ASJC Scopus subject areas
- Food Science
- Toxicology