Rhodamine analogs for molecular ruler applications

Yu Hsuan Chu; Jorge O. Escobedo; Meiyan Jiang; Peter S. Steyger; Robert M. Strongin

doi:10.1016/j.dyepig.2015.11.015

Rhodamine analogs for molecular ruler applications

Yu Hsuan Chu, Jorge O. Escobedo, Meiyan Jiang, Peter S. Steyger, Robert M. Strongin

Otolaryngology

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

A series of geometrically well-defined cationic fluorophores were designed based on molecular mechanics. They contain biaryl linkers to impart rigidity preventing intramolecular folding between a conjugated biomolecule and fluorophore. All probes have absorption and emission maxima within 20 nm from Texas Red, as predicted by TDDFT calculations and validated experimentally.

Original language	English (US)
Pages (from-to)	46-53
Number of pages	8
Journal	Dyes and Pigments
Volume	126
DOIs	https://doi.org/10.1016/j.dyepig.2015.11.015
State	Published - Mar 1 2016

Keywords

Ion channel
Molecular ruler
Near-infrared
Pore dilation
Rhodamine
Texas red

ASJC Scopus subject areas

General Chemical Engineering
Process Chemistry and Technology

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10.1016/j.dyepig.2015.11.015

Cite this

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title = "Rhodamine analogs for molecular ruler applications",

abstract = "A series of geometrically well-defined cationic fluorophores were designed based on molecular mechanics. They contain biaryl linkers to impart rigidity preventing intramolecular folding between a conjugated biomolecule and fluorophore. All probes have absorption and emission maxima within 20 nm from Texas Red, as predicted by TDDFT calculations and validated experimentally.",

keywords = "Ion channel, Molecular ruler, Near-infrared, Pore dilation, Rhodamine, Texas red",

author = "Chu, {Yu Hsuan} and Escobedo, {Jorge O.} and Meiyan Jiang and Steyger, {Peter S.} and Strongin, {Robert M.}",

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doi = "10.1016/j.dyepig.2015.11.015",

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T1 - Rhodamine analogs for molecular ruler applications

AU - Chu, Yu Hsuan

AU - Escobedo, Jorge O.

AU - Jiang, Meiyan

AU - Steyger, Peter S.

AU - Strongin, Robert M.

PY - 2016/3/1

Y1 - 2016/3/1

N2 - A series of geometrically well-defined cationic fluorophores were designed based on molecular mechanics. They contain biaryl linkers to impart rigidity preventing intramolecular folding between a conjugated biomolecule and fluorophore. All probes have absorption and emission maxima within 20 nm from Texas Red, as predicted by TDDFT calculations and validated experimentally.

AB - A series of geometrically well-defined cationic fluorophores were designed based on molecular mechanics. They contain biaryl linkers to impart rigidity preventing intramolecular folding between a conjugated biomolecule and fluorophore. All probes have absorption and emission maxima within 20 nm from Texas Red, as predicted by TDDFT calculations and validated experimentally.

KW - Ion channel

KW - Molecular ruler

KW - Near-infrared

KW - Pore dilation

KW - Rhodamine

KW - Texas red

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U2 - 10.1016/j.dyepig.2015.11.015

DO - 10.1016/j.dyepig.2015.11.015

M3 - Article

AN - SCOPUS:84949571036

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VL - 126

SP - 46

EP - 53

JO - Dyes and Pigments

JF - Dyes and Pigments

ER -

Rhodamine analogs for molecular ruler applications

Abstract

Keywords

ASJC Scopus subject areas

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