Rhodamine analogs for molecular ruler applications

Yu Hsuan Chu, Jorge O. Escobedo, Meiyan Jiang, Peter S. Steyger, Robert M. Strongin

Research output: Contribution to journalArticle

3 Scopus citations


A series of geometrically well-defined cationic fluorophores were designed based on molecular mechanics. They contain biaryl linkers to impart rigidity preventing intramolecular folding between a conjugated biomolecule and fluorophore. All probes have absorption and emission maxima within 20 nm from Texas Red, as predicted by TDDFT calculations and validated experimentally.

Original languageEnglish (US)
Pages (from-to)46-53
Number of pages8
JournalDyes and Pigments
StatePublished - Mar 1 2016


  • Ion channel
  • Molecular ruler
  • Near-infrared
  • Pore dilation
  • Rhodamine
  • Texas red

ASJC Scopus subject areas

  • Chemical Engineering(all)
  • Process Chemistry and Technology

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    Chu, Y. H., Escobedo, J. O., Jiang, M., Steyger, P. S., & Strongin, R. M. (2016). Rhodamine analogs for molecular ruler applications. Dyes and Pigments, 126, 46-53. https://doi.org/10.1016/j.dyepig.2015.11.015