Rheumatoid nodule presenting as a buccal submucosal nodule: A rare presentation of a common disease

Gerald Ci An Tay, David Sauer, Peter Andersen, Jonathan Irish

Research output: Contribution to journalArticle

2 Scopus citations


Background: Rheumatoid nodules are a common manifestation of rheumatoid arthritis but buccal rheumatoid nodules are extremely rare. The purpose of this study was to report a rare case of a rheumatoid buccal nodule and a review of the literature. Methods and Results: This case is about a 79-year-old woman with rheumatoid arthritis who was taking methotrexate and hydroxychloroquine, presenting with an enlarging left buccal submucosal mass. An incisional biopsy showed features consistent with that of a rheumatoid nodule. The mass was managed expectantly and the patient was taken off methotrexate with a marked reduction in the size of the nodule. Conclusion: Submucosal rheumatoid nodules of the oral cavity are an extremely rare manifestation of rheumatoid arthritis but should be considered in the differential diagnosis in patients with a history of rheumatoid arthritis presenting with submucosal masses.

Original languageEnglish (US)
Pages (from-to)E12-E14
JournalHead and Neck
Issue number1
StatePublished - Jan 1 2017



  • autoimmune
  • buccal mass
  • methotrexate
  • rheumatoid arthritis
  • rheumatoid nodule

ASJC Scopus subject areas

  • Otorhinolaryngology

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