Rhabdomyosarcoma: Review of the Children's Oncology Group (COG) soft-tissue Sarcoma committee experience and rationale for current COG studies

Suman Malempati, Douglas S. Hawkins

Research output: Contribution to journalReview article

182 Scopus citations


The prognosis for children and adolescents with rhabdomyosarcoma (RMS) has improved with refinements in multi-modal therapy. Since 1972, the Intergroup Rhabdomyosarcoma Study Group (now the Children's Oncology Group Soft-Tissue Sarcoma Committee) has conducted serial studies for RMS. This review describes the IRSG and COG experience with RMS, presents the current risk stratification definitions, and provides rationale for the current generation of COG RMS studies.

Original languageEnglish (US)
Pages (from-to)5-10
Number of pages6
JournalPediatric Blood and Cancer
Issue number1
StatePublished - Jul 15 2012



  • Pediatric
  • Rhabdomyosarcoma
  • Soft-tissue sarcoma

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

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