Retrograde Insufflation of Gaseous Oxygen into the Coronary Sinus as a Means of Myocardial Maintenance

A. Hedley Brown, Nelson R. Niles, Mark V. Braimbridge, W. Gerald Austen

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Isolated canine hearts were used to evaluate retrograde gaseous oxygen perfusion of the heart as a method of preservation at room temperature for three hours compared with continuous normothermic cross-perfusion, ischemia at room temperature, and ischemia at 4 C, assessing the myocardium by functional, histochemical, and birefringence techniques. Statistically demonstrable benefit of oxygen insufflation over three hours of ischemia at the same temperature could be shown histochemically and there was also a trend toward functional benefit from this technique.

Original languageEnglish (US)
Pages (from-to)622-627
Number of pages6
JournalArchives of Surgery
Volume105
Issue number4
DOIs
StatePublished - Oct 1972
Externally publishedYes

ASJC Scopus subject areas

  • Surgery

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