Retinoid therapy is associated with excess granulation tissue responses

Janis P. Campbell; Roy C. Grekin; Charles N. Ellis; Stella S. Matsuda-John; Neil A. Swanson; John J. Voorhees

doi:10.1016/S0190-9622(83)70184-2

Retinoid therapy is associated with excess granulation tissue responses

Janis P. Campbell, Roy C. Grekin, Charles N. Ellis, Stella S. Matsuda-John, Neil A. Swanson, John J. Voorhees

Research output: Contribution to journal › Article › peer-review

80 Scopus citations

Abstract

In our clinical trials of isotretinoin therapy for cystic acne and etretinate treatment of psoriasis, eight patients had growth of excessive granulation tissue. The granulation tissue was found in resolving acne lesions in one patient taking isotretinoin. Among the psoriatic patients taking etretinate, the granulation tissue usually was seen adjacent to nail plates. In two patients, the side effect caused them to stop retinoid therapy. The tissue response did not appear to be related to the daily or cumulative retinoid dose.

Original language	English (US)
Pages (from-to)	708-713
Number of pages	6
Journal	Journal of the American Academy of Dermatology
Volume	9
Issue number	5
DOIs	https://doi.org/10.1016/S0190-9622(83)70184-2
State	Published - 1983
Externally published	Yes

ASJC Scopus subject areas

Dermatology

Access to Document

10.1016/S0190-9622(83)70184-2

Cite this

@article{6d247c12fcc4492cb88a48c172ea4d40,

title = "Retinoid therapy is associated with excess granulation tissue responses",

abstract = "In our clinical trials of isotretinoin therapy for cystic acne and etretinate treatment of psoriasis, eight patients had growth of excessive granulation tissue. The granulation tissue was found in resolving acne lesions in one patient taking isotretinoin. Among the psoriatic patients taking etretinate, the granulation tissue usually was seen adjacent to nail plates. In two patients, the side effect caused them to stop retinoid therapy. The tissue response did not appear to be related to the daily or cumulative retinoid dose.",

author = "Campbell, {Janis P.} and Grekin, {Roy C.} and Ellis, {Charles N.} and Matsuda-John, {Stella S.} and Swanson, {Neil A.} and Voorhees, {John J.}",

year = "1983",

doi = "10.1016/S0190-9622(83)70184-2",

language = "English (US)",

volume = "9",

pages = "708--713",

journal = "Journal of the American Academy of Dermatology",

issn = "0190-9622",

publisher = "Mosby Inc.",

number = "5",

}

TY - JOUR

T1 - Retinoid therapy is associated with excess granulation tissue responses

AU - Campbell, Janis P.

AU - Grekin, Roy C.

AU - Ellis, Charles N.

AU - Matsuda-John, Stella S.

AU - Swanson, Neil A.

AU - Voorhees, John J.

PY - 1983

Y1 - 1983

N2 - In our clinical trials of isotretinoin therapy for cystic acne and etretinate treatment of psoriasis, eight patients had growth of excessive granulation tissue. The granulation tissue was found in resolving acne lesions in one patient taking isotretinoin. Among the psoriatic patients taking etretinate, the granulation tissue usually was seen adjacent to nail plates. In two patients, the side effect caused them to stop retinoid therapy. The tissue response did not appear to be related to the daily or cumulative retinoid dose.

AB - In our clinical trials of isotretinoin therapy for cystic acne and etretinate treatment of psoriasis, eight patients had growth of excessive granulation tissue. The granulation tissue was found in resolving acne lesions in one patient taking isotretinoin. Among the psoriatic patients taking etretinate, the granulation tissue usually was seen adjacent to nail plates. In two patients, the side effect caused them to stop retinoid therapy. The tissue response did not appear to be related to the daily or cumulative retinoid dose.

UR - http://www.scopus.com/inward/record.url?scp=0021085435&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021085435&partnerID=8YFLogxK

U2 - 10.1016/S0190-9622(83)70184-2

DO - 10.1016/S0190-9622(83)70184-2

M3 - Article

C2 - 6227639

AN - SCOPUS:0021085435

SN - 0190-9622

VL - 9

SP - 708

EP - 713

JO - Journal of the American Academy of Dermatology

JF - Journal of the American Academy of Dermatology

IS - 5

ER -

Retinoid therapy is associated with excess granulation tissue responses

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this