Retinoblastoma-related proteins in plants: Homologues or orthologues of their metazoan counterparts?

T. Durfee, H. S. Feiler, W. Gruissem

Research output: Contribution to journalArticlepeer-review

53 Scopus citations


The mammalian retinoblastoma tumor suppressor protein (prb) regulates cell division, differentiation and apoptotic pathways in specific cell types. In association with other proteins, prb acts in part by modulating transcriptional activity. Elements of the prb regulatory network have been identified in higher plants. Recent findings involving these proteins, which display amino acid sequence homology and biochemical binding properties analogous to their mammalian counterparts, are discussed.

Original languageEnglish (US)
Pages (from-to)635-642
Number of pages8
JournalPlant Molecular Biology
Issue number5-6
StatePublished - Jan 1 2000
Externally publishedYes


  • Plant cell cycle
  • RBR
  • Retinoblastoma

ASJC Scopus subject areas

  • Agronomy and Crop Science
  • Genetics
  • Plant Science


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