Retinoblastoma-related proteins in plants: Homologues or orthologues of their metazoan counterparts?

T. Durfee, Heidi Feiler, W. Gruissem

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

The mammalian retinoblastoma tumor suppressor protein (prb) regulates cell division, differentiation and apoptotic pathways in specific cell types. In association with other proteins, prb acts in part by modulating transcriptional activity. Elements of the prb regulatory network have been identified in higher plants. Recent findings involving these proteins, which display amino acid sequence homology and biochemical binding properties analogous to their mammalian counterparts, are discussed.

Original languageEnglish (US)
Pages (from-to)635-642
Number of pages8
JournalPlant Molecular Biology
Volume43
Issue number5-6
StatePublished - 2000
Externally publishedYes

Fingerprint

Retinoblastoma Protein
plant proteins
Tumor Suppressor Proteins
Amino Acid Sequence Homology
binding properties
sequence homology
Cell Division
cell division
Cell Differentiation
Proteins
amino acid sequences
proteins
Cells
Amino Acids
cells
tumor suppressor proteins

Keywords

  • Plant cell cycle
  • RBR
  • Retinoblastoma

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry

Cite this

Retinoblastoma-related proteins in plants : Homologues or orthologues of their metazoan counterparts? / Durfee, T.; Feiler, Heidi; Gruissem, W.

In: Plant Molecular Biology, Vol. 43, No. 5-6, 2000, p. 635-642.

Research output: Contribution to journalArticle

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