Retinoblastoma-related proteins in plants: Homologues or orthologues of their metazoan counterparts?

T. Durfee; H. S. Feiler; W. Gruissem

doi:10.1023/a:1006426808185

Retinoblastoma-related proteins in plants: Homologues or orthologues of their metazoan counterparts?

T. Durfee, H. S. Feiler, W. Gruissem

Research output: Contribution to journal › Article › peer-review

53 Scopus citations

Abstract

The mammalian retinoblastoma tumor suppressor protein (prb) regulates cell division, differentiation and apoptotic pathways in specific cell types. In association with other proteins, prb acts in part by modulating transcriptional activity. Elements of the prb regulatory network have been identified in higher plants. Recent findings involving these proteins, which display amino acid sequence homology and biochemical binding properties analogous to their mammalian counterparts, are discussed.

Original language	English (US)
Pages (from-to)	635-642
Number of pages	8
Journal	Plant Molecular Biology
Volume	43
Issue number	5-6
DOIs	https://doi.org/10.1023/a:1006426808185
State	Published - Jan 1 2000
Externally published	Yes

Keywords

Plant cell cycle
RBR
Retinoblastoma

ASJC Scopus subject areas

Agronomy and Crop Science
Genetics
Plant Science

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10.1023/a:1006426808185

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title = "Retinoblastoma-related proteins in plants: Homologues or orthologues of their metazoan counterparts?",

abstract = "The mammalian retinoblastoma tumor suppressor protein (prb) regulates cell division, differentiation and apoptotic pathways in specific cell types. In association with other proteins, prb acts in part by modulating transcriptional activity. Elements of the prb regulatory network have been identified in higher plants. Recent findings involving these proteins, which display amino acid sequence homology and biochemical binding properties analogous to their mammalian counterparts, are discussed.",

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year = "2000",

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T2 - Homologues or orthologues of their metazoan counterparts?

AU - Durfee, T.

AU - Feiler, H. S.

AU - Gruissem, W.

PY - 2000/1/1

Y1 - 2000/1/1

N2 - The mammalian retinoblastoma tumor suppressor protein (prb) regulates cell division, differentiation and apoptotic pathways in specific cell types. In association with other proteins, prb acts in part by modulating transcriptional activity. Elements of the prb regulatory network have been identified in higher plants. Recent findings involving these proteins, which display amino acid sequence homology and biochemical binding properties analogous to their mammalian counterparts, are discussed.

AB - The mammalian retinoblastoma tumor suppressor protein (prb) regulates cell division, differentiation and apoptotic pathways in specific cell types. In association with other proteins, prb acts in part by modulating transcriptional activity. Elements of the prb regulatory network have been identified in higher plants. Recent findings involving these proteins, which display amino acid sequence homology and biochemical binding properties analogous to their mammalian counterparts, are discussed.

KW - Plant cell cycle

KW - RBR

KW - Retinoblastoma

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ER -

Retinoblastoma-related proteins in plants: Homologues or orthologues of their metazoan counterparts?

Abstract

Keywords

ASJC Scopus subject areas

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