Rest-activity cycle and melatonin rhythm in blind free-runners have similar periods

Jonathan Emens, Alfred Lewy, Amber L. Laurie, Jeannie B. Songer

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

In the absence of the entraining light-dark cycle, most totally blind humans free-run, albeit with relative coordination to nonphotic zeitgebers. Such blind free-runners (BFRs) often attempt to maintain a 24-h sleep-wake schedule and consequently suffer from recurrent sleep disruption and daytime somnolence. This study was conducted to determine the periods of the free-running melatonin rhythm and of the rest-activity cycle in 16 BFRs. It was found that the non-24-h component of the rest-activity rhythm correlated with the observed period of the circadian pacemaker.

Original languageEnglish (US)
Pages (from-to)381-384
Number of pages4
JournalJournal of Biological Rhythms
Volume25
Issue number5
DOIs
StatePublished - Oct 2010

Fingerprint

Activity Cycles
Melatonin
Sleep
Photoperiod
Running
Appointments and Schedules

Keywords

  • blindness
  • circadian
  • entrainment
  • human
  • melatonin
  • relative coordination

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)

Cite this

Rest-activity cycle and melatonin rhythm in blind free-runners have similar periods. / Emens, Jonathan; Lewy, Alfred; Laurie, Amber L.; Songer, Jeannie B.

In: Journal of Biological Rhythms, Vol. 25, No. 5, 10.2010, p. 381-384.

Research output: Contribution to journalArticle

Emens, Jonathan ; Lewy, Alfred ; Laurie, Amber L. ; Songer, Jeannie B. / Rest-activity cycle and melatonin rhythm in blind free-runners have similar periods. In: Journal of Biological Rhythms. 2010 ; Vol. 25, No. 5. pp. 381-384.
@article{2ab606a44676444d910e2d8cd6699002,
title = "Rest-activity cycle and melatonin rhythm in blind free-runners have similar periods",
abstract = "In the absence of the entraining light-dark cycle, most totally blind humans free-run, albeit with relative coordination to nonphotic zeitgebers. Such blind free-runners (BFRs) often attempt to maintain a 24-h sleep-wake schedule and consequently suffer from recurrent sleep disruption and daytime somnolence. This study was conducted to determine the periods of the free-running melatonin rhythm and of the rest-activity cycle in 16 BFRs. It was found that the non-24-h component of the rest-activity rhythm correlated with the observed period of the circadian pacemaker.",
keywords = "blindness, circadian, entrainment, human, melatonin, relative coordination",
author = "Jonathan Emens and Alfred Lewy and Laurie, {Amber L.} and Songer, {Jeannie B.}",
year = "2010",
month = "10",
doi = "10.1177/0748730410379080",
language = "English (US)",
volume = "25",
pages = "381--384",
journal = "Journal of Biological Rhythms",
issn = "0748-7304",
publisher = "SAGE Publications Inc.",
number = "5",

}

TY - JOUR

T1 - Rest-activity cycle and melatonin rhythm in blind free-runners have similar periods

AU - Emens, Jonathan

AU - Lewy, Alfred

AU - Laurie, Amber L.

AU - Songer, Jeannie B.

PY - 2010/10

Y1 - 2010/10

N2 - In the absence of the entraining light-dark cycle, most totally blind humans free-run, albeit with relative coordination to nonphotic zeitgebers. Such blind free-runners (BFRs) often attempt to maintain a 24-h sleep-wake schedule and consequently suffer from recurrent sleep disruption and daytime somnolence. This study was conducted to determine the periods of the free-running melatonin rhythm and of the rest-activity cycle in 16 BFRs. It was found that the non-24-h component of the rest-activity rhythm correlated with the observed period of the circadian pacemaker.

AB - In the absence of the entraining light-dark cycle, most totally blind humans free-run, albeit with relative coordination to nonphotic zeitgebers. Such blind free-runners (BFRs) often attempt to maintain a 24-h sleep-wake schedule and consequently suffer from recurrent sleep disruption and daytime somnolence. This study was conducted to determine the periods of the free-running melatonin rhythm and of the rest-activity cycle in 16 BFRs. It was found that the non-24-h component of the rest-activity rhythm correlated with the observed period of the circadian pacemaker.

KW - blindness

KW - circadian

KW - entrainment

KW - human

KW - melatonin

KW - relative coordination

UR - http://www.scopus.com/inward/record.url?scp=77957256608&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77957256608&partnerID=8YFLogxK

U2 - 10.1177/0748730410379080

DO - 10.1177/0748730410379080

M3 - Article

C2 - 20876818

AN - SCOPUS:77957256608

VL - 25

SP - 381

EP - 384

JO - Journal of Biological Rhythms

JF - Journal of Biological Rhythms

SN - 0748-7304

IS - 5

ER -