Responses of cultured adult monkey trigeminal ganglion neurons to capsaicin

Susan L. Ingram, Melissa E. Martenson, Thomas K. Baumann

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

The sensitivity of adult primate (Macaca mulatto) trigeminal ganglion neurons to capsaicin was studied using whole-cell recording techniques. Neurons responding to capsaicin (9 out of 14) generated inward currents of up to 3.0 nA (median = 0.23 nA; interquartile range = 1.19 nA) upon drug application measured at — 60 mV. Capsaicin-sensitive neurons had longer action potential (AP) durations than capsaicin-insensitive neurons.

Original languageEnglish (US)
Pages (from-to)460-462
Number of pages3
JournalNeuroReport
Volume4
Issue number4
DOIs
StatePublished - Apr 1993

Keywords

  • Action potential
  • Capsaicin
  • Chemosensitivity
  • Irritant
  • Macaca mulatta
  • Pain
  • Patch clamp
  • Trigeminal ganglion

ASJC Scopus subject areas

  • Neuroscience(all)

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