Respiratory Virus Infections of the Stem Cell Transplant Recipient and the Hematologic Malignancy Patient

Lauren Fontana, Lynne Strasfeld

Research output: Contribution to journalReview article

Abstract

Respiratory virus infections in hematologic stem cell transplant recipients and patients with hematologic malignancies are increasingly recognized as a cause of significant morbidity and mortality. The often overlapping clinical presentation makes molecular diagnostic strategies imperative for rapid diagnosis and to inform understanding of the changing epidemiology of each of the respiratory viruses. Most respiratory virus infections are managed with supportive therapy, although there is effective antiviral therapy for influenza. The primary focus should remain on primary prevention infection control procedures and isolation precautions, avoidance of ill contacts, and vaccination for influenza.

Original languageEnglish (US)
JournalInfectious Disease Clinics of North America
DOIs
StatePublished - Jan 1 2019

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Virus Diseases
Hematologic Neoplasms
Respiratory Tract Infections
Human Influenza
Stem Cells
Transplants
Molecular Pathology
Primary Prevention
Infection Control
Antiviral Agents
Vaccination
Epidemiology
Viruses
Morbidity
Mortality
Therapeutics
Transplant Recipients

Keywords

  • Coronavirus
  • Hematopoietic stem cell transplant
  • Human metapneumovirus
  • Influenza
  • Parainfluenza
  • Respiratory virus infection
  • Rhinovirus
  • RSV

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

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abstract = "Respiratory virus infections in hematologic stem cell transplant recipients and patients with hematologic malignancies are increasingly recognized as a cause of significant morbidity and mortality. The often overlapping clinical presentation makes molecular diagnostic strategies imperative for rapid diagnosis and to inform understanding of the changing epidemiology of each of the respiratory viruses. Most respiratory virus infections are managed with supportive therapy, although there is effective antiviral therapy for influenza. The primary focus should remain on primary prevention infection control procedures and isolation precautions, avoidance of ill contacts, and vaccination for influenza.",
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AB - Respiratory virus infections in hematologic stem cell transplant recipients and patients with hematologic malignancies are increasingly recognized as a cause of significant morbidity and mortality. The often overlapping clinical presentation makes molecular diagnostic strategies imperative for rapid diagnosis and to inform understanding of the changing epidemiology of each of the respiratory viruses. Most respiratory virus infections are managed with supportive therapy, although there is effective antiviral therapy for influenza. The primary focus should remain on primary prevention infection control procedures and isolation precautions, avoidance of ill contacts, and vaccination for influenza.

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KW - RSV

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