Report of the NIH task force on research standards for chronic low back pain

Richard (Rick) Deyo, Samuel F. Dworkin, Dagmar Amtmann, Gunnar Andersson, David Borenstein, Eugene Carragee, John Carrino, Roger Chou, Karon Cook, Anthony Delitto, Christine Goertz, Partap Khalsa, John Loeser, Sean MacKey, James Panagis, James Rainville, Tor Tosteson, Dennis Turk, Michael Von Korff, Debra K. Weiner

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Despite rapidly increasing intervention, functional disability due to chronic low back pain (cLBP) has increased in recent decades. We often cannot identify mechanisms to explain the major negative impact cLBP has on patients' lives. Such cLBP is often termed non-specific and may be due to multiple biologic and behavioral etiologies. Researchers use varied inclusion criteria, definitions, baseline assessments, and outcome measures, which impede comparisons and consensus. Therefore, NIH Pain Consortium charged a Research Task Force (RTF) to draft standards for research on cLBP. The resulting multidisciplinary panel recommended using 2 questions to define cLBP; classifying cLBP by its impact (defined by pain intensity, pain interference, and physical function); use of a minimum dataset to describe research participants (drawing heavily on the PROMIS methodology); reporting "responder analyses" in addition to mean outcome scores; and suggestions for future research and dissemination. The Pain Consortium has approved the recommendations, which investigators should incorporate into NIH grant proposals. The RTF believes that these recommendations will advance the field, help to resolve controversies, and facilitate future research addressing the genomic, neurologic, and other mechanistic substrates of chronic low back pain. We expect that the RTF recommendations will become a dynamic document and undergo continual improvement. Perspective A task force was convened by the NIH Pain Consortium with the goal of developing research standards for chronic low back pain. The results included recommendations for definitions, a minimum dataset, reporting outcomes, and future research. Greater consistency in reporting should facilitate comparisons among studies and the development of phenotypes.

Original languageEnglish (US)
Pages (from-to)1375-1391
Number of pages17
JournalSpine Journal
Volume14
Issue number8
DOIs
StatePublished - Aug 1 2014

Fingerprint

Advisory Committees
Low Back Pain
Research
Pain
Research Personnel
Organized Financing
Nervous System
Consensus
Outcome Assessment (Health Care)
Phenotype

Keywords

  • chronic low back pain
  • Low back pain
  • minimum dataset
  • NIH Task Force
  • research standards

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Deyo, R. R., Dworkin, S. F., Amtmann, D., Andersson, G., Borenstein, D., Carragee, E., ... Weiner, D. K. (2014). Report of the NIH task force on research standards for chronic low back pain. Spine Journal, 14(8), 1375-1391. https://doi.org/10.1016/j.spinee.2014.05.002

Report of the NIH task force on research standards for chronic low back pain. / Deyo, Richard (Rick); Dworkin, Samuel F.; Amtmann, Dagmar; Andersson, Gunnar; Borenstein, David; Carragee, Eugene; Carrino, John; Chou, Roger; Cook, Karon; Delitto, Anthony; Goertz, Christine; Khalsa, Partap; Loeser, John; MacKey, Sean; Panagis, James; Rainville, James; Tosteson, Tor; Turk, Dennis; Von Korff, Michael; Weiner, Debra K.

In: Spine Journal, Vol. 14, No. 8, 01.08.2014, p. 1375-1391.

Research output: Contribution to journalArticle

Deyo, RR, Dworkin, SF, Amtmann, D, Andersson, G, Borenstein, D, Carragee, E, Carrino, J, Chou, R, Cook, K, Delitto, A, Goertz, C, Khalsa, P, Loeser, J, MacKey, S, Panagis, J, Rainville, J, Tosteson, T, Turk, D, Von Korff, M & Weiner, DK 2014, 'Report of the NIH task force on research standards for chronic low back pain', Spine Journal, vol. 14, no. 8, pp. 1375-1391. https://doi.org/10.1016/j.spinee.2014.05.002
Deyo RR, Dworkin SF, Amtmann D, Andersson G, Borenstein D, Carragee E et al. Report of the NIH task force on research standards for chronic low back pain. Spine Journal. 2014 Aug 1;14(8):1375-1391. https://doi.org/10.1016/j.spinee.2014.05.002
Deyo, Richard (Rick) ; Dworkin, Samuel F. ; Amtmann, Dagmar ; Andersson, Gunnar ; Borenstein, David ; Carragee, Eugene ; Carrino, John ; Chou, Roger ; Cook, Karon ; Delitto, Anthony ; Goertz, Christine ; Khalsa, Partap ; Loeser, John ; MacKey, Sean ; Panagis, James ; Rainville, James ; Tosteson, Tor ; Turk, Dennis ; Von Korff, Michael ; Weiner, Debra K. / Report of the NIH task force on research standards for chronic low back pain. In: Spine Journal. 2014 ; Vol. 14, No. 8. pp. 1375-1391.
@article{3543a944774e4d19aeec4e8cabf76e9a,
title = "Report of the NIH task force on research standards for chronic low back pain",
abstract = "Despite rapidly increasing intervention, functional disability due to chronic low back pain (cLBP) has increased in recent decades. We often cannot identify mechanisms to explain the major negative impact cLBP has on patients' lives. Such cLBP is often termed non-specific and may be due to multiple biologic and behavioral etiologies. Researchers use varied inclusion criteria, definitions, baseline assessments, and outcome measures, which impede comparisons and consensus. Therefore, NIH Pain Consortium charged a Research Task Force (RTF) to draft standards for research on cLBP. The resulting multidisciplinary panel recommended using 2 questions to define cLBP; classifying cLBP by its impact (defined by pain intensity, pain interference, and physical function); use of a minimum dataset to describe research participants (drawing heavily on the PROMIS methodology); reporting {"}responder analyses{"} in addition to mean outcome scores; and suggestions for future research and dissemination. The Pain Consortium has approved the recommendations, which investigators should incorporate into NIH grant proposals. The RTF believes that these recommendations will advance the field, help to resolve controversies, and facilitate future research addressing the genomic, neurologic, and other mechanistic substrates of chronic low back pain. We expect that the RTF recommendations will become a dynamic document and undergo continual improvement. Perspective A task force was convened by the NIH Pain Consortium with the goal of developing research standards for chronic low back pain. The results included recommendations for definitions, a minimum dataset, reporting outcomes, and future research. Greater consistency in reporting should facilitate comparisons among studies and the development of phenotypes.",
keywords = "chronic low back pain, Low back pain, minimum dataset, NIH Task Force, research standards",
author = "Deyo, {Richard (Rick)} and Dworkin, {Samuel F.} and Dagmar Amtmann and Gunnar Andersson and David Borenstein and Eugene Carragee and John Carrino and Roger Chou and Karon Cook and Anthony Delitto and Christine Goertz and Partap Khalsa and John Loeser and Sean MacKey and James Panagis and James Rainville and Tor Tosteson and Dennis Turk and {Von Korff}, Michael and Weiner, {Debra K.}",
year = "2014",
month = "8",
day = "1",
doi = "10.1016/j.spinee.2014.05.002",
language = "English (US)",
volume = "14",
pages = "1375--1391",
journal = "Spine Journal",
issn = "1529-9430",
publisher = "Elsevier Inc.",
number = "8",

}

TY - JOUR

T1 - Report of the NIH task force on research standards for chronic low back pain

AU - Deyo, Richard (Rick)

AU - Dworkin, Samuel F.

AU - Amtmann, Dagmar

AU - Andersson, Gunnar

AU - Borenstein, David

AU - Carragee, Eugene

AU - Carrino, John

AU - Chou, Roger

AU - Cook, Karon

AU - Delitto, Anthony

AU - Goertz, Christine

AU - Khalsa, Partap

AU - Loeser, John

AU - MacKey, Sean

AU - Panagis, James

AU - Rainville, James

AU - Tosteson, Tor

AU - Turk, Dennis

AU - Von Korff, Michael

AU - Weiner, Debra K.

PY - 2014/8/1

Y1 - 2014/8/1

N2 - Despite rapidly increasing intervention, functional disability due to chronic low back pain (cLBP) has increased in recent decades. We often cannot identify mechanisms to explain the major negative impact cLBP has on patients' lives. Such cLBP is often termed non-specific and may be due to multiple biologic and behavioral etiologies. Researchers use varied inclusion criteria, definitions, baseline assessments, and outcome measures, which impede comparisons and consensus. Therefore, NIH Pain Consortium charged a Research Task Force (RTF) to draft standards for research on cLBP. The resulting multidisciplinary panel recommended using 2 questions to define cLBP; classifying cLBP by its impact (defined by pain intensity, pain interference, and physical function); use of a minimum dataset to describe research participants (drawing heavily on the PROMIS methodology); reporting "responder analyses" in addition to mean outcome scores; and suggestions for future research and dissemination. The Pain Consortium has approved the recommendations, which investigators should incorporate into NIH grant proposals. The RTF believes that these recommendations will advance the field, help to resolve controversies, and facilitate future research addressing the genomic, neurologic, and other mechanistic substrates of chronic low back pain. We expect that the RTF recommendations will become a dynamic document and undergo continual improvement. Perspective A task force was convened by the NIH Pain Consortium with the goal of developing research standards for chronic low back pain. The results included recommendations for definitions, a minimum dataset, reporting outcomes, and future research. Greater consistency in reporting should facilitate comparisons among studies and the development of phenotypes.

AB - Despite rapidly increasing intervention, functional disability due to chronic low back pain (cLBP) has increased in recent decades. We often cannot identify mechanisms to explain the major negative impact cLBP has on patients' lives. Such cLBP is often termed non-specific and may be due to multiple biologic and behavioral etiologies. Researchers use varied inclusion criteria, definitions, baseline assessments, and outcome measures, which impede comparisons and consensus. Therefore, NIH Pain Consortium charged a Research Task Force (RTF) to draft standards for research on cLBP. The resulting multidisciplinary panel recommended using 2 questions to define cLBP; classifying cLBP by its impact (defined by pain intensity, pain interference, and physical function); use of a minimum dataset to describe research participants (drawing heavily on the PROMIS methodology); reporting "responder analyses" in addition to mean outcome scores; and suggestions for future research and dissemination. The Pain Consortium has approved the recommendations, which investigators should incorporate into NIH grant proposals. The RTF believes that these recommendations will advance the field, help to resolve controversies, and facilitate future research addressing the genomic, neurologic, and other mechanistic substrates of chronic low back pain. We expect that the RTF recommendations will become a dynamic document and undergo continual improvement. Perspective A task force was convened by the NIH Pain Consortium with the goal of developing research standards for chronic low back pain. The results included recommendations for definitions, a minimum dataset, reporting outcomes, and future research. Greater consistency in reporting should facilitate comparisons among studies and the development of phenotypes.

KW - chronic low back pain

KW - Low back pain

KW - minimum dataset

KW - NIH Task Force

KW - research standards

UR - http://www.scopus.com/inward/record.url?scp=84905494061&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84905494061&partnerID=8YFLogxK

U2 - 10.1016/j.spinee.2014.05.002

DO - 10.1016/j.spinee.2014.05.002

M3 - Article

C2 - 24950669

AN - SCOPUS:84905494061

VL - 14

SP - 1375

EP - 1391

JO - Spine Journal

JF - Spine Journal

SN - 1529-9430

IS - 8

ER -