Replacement of methoxatin by 4,7-phenanthroline-5,6-dione and the inability of other phenanthroline quinones, as well as 7,9-di-decarboxy methoxatin, to serve as cofactors for the methoxatin-requiring glucose dehydrogenase of Acinetobacter calcoaceticus

Michael Conlin, H. S. Forrest, Thomas C. Bruice

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Glucose dehydrogenase from A. calcoaceticus has been dissociated into apoenzyme and methoxatin coenzyme, and enzyme activity restored by replacing coenzyme with 4,7-phenanthroline-5,6-dione but not with 1,10- nor 1,7-phenanthroline-5,6-diones nor with 7,9-decarboxy methoxatin.

Original languageEnglish (US)
Pages (from-to)564-566
Number of pages3
JournalBiochemical and Biophysical Research Communications
Volume131
Issue number2
DOIs
StatePublished - Sep 16 1985
Externally publishedYes

Fingerprint

PQQ Cofactor
Glucose 1-Dehydrogenase
Acinetobacter calcoaceticus
Quinones
Phenanthrolines
Enzymes and Coenzymes
Apoenzymes
Coenzymes
Enzyme activity
7,9-di-decarboxy methoxatin
phanquinone

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

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title = "Replacement of methoxatin by 4,7-phenanthroline-5,6-dione and the inability of other phenanthroline quinones, as well as 7,9-di-decarboxy methoxatin, to serve as cofactors for the methoxatin-requiring glucose dehydrogenase of Acinetobacter calcoaceticus",
abstract = "Glucose dehydrogenase from A. calcoaceticus has been dissociated into apoenzyme and methoxatin coenzyme, and enzyme activity restored by replacing coenzyme with 4,7-phenanthroline-5,6-dione but not with 1,10- nor 1,7-phenanthroline-5,6-diones nor with 7,9-decarboxy methoxatin.",
author = "Michael Conlin and Forrest, {H. S.} and Bruice, {Thomas C.}",
year = "1985",
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doi = "10.1016/0006-291X(85)91273-2",
language = "English (US)",
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journal = "Biochemical and Biophysical Research Communications",
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TY - JOUR

T1 - Replacement of methoxatin by 4,7-phenanthroline-5,6-dione and the inability of other phenanthroline quinones, as well as 7,9-di-decarboxy methoxatin, to serve as cofactors for the methoxatin-requiring glucose dehydrogenase of Acinetobacter calcoaceticus

AU - Conlin, Michael

AU - Forrest, H. S.

AU - Bruice, Thomas C.

PY - 1985/9/16

Y1 - 1985/9/16

N2 - Glucose dehydrogenase from A. calcoaceticus has been dissociated into apoenzyme and methoxatin coenzyme, and enzyme activity restored by replacing coenzyme with 4,7-phenanthroline-5,6-dione but not with 1,10- nor 1,7-phenanthroline-5,6-diones nor with 7,9-decarboxy methoxatin.

AB - Glucose dehydrogenase from A. calcoaceticus has been dissociated into apoenzyme and methoxatin coenzyme, and enzyme activity restored by replacing coenzyme with 4,7-phenanthroline-5,6-dione but not with 1,10- nor 1,7-phenanthroline-5,6-diones nor with 7,9-decarboxy methoxatin.

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U2 - 10.1016/0006-291X(85)91273-2

DO - 10.1016/0006-291X(85)91273-2

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JO - Biochemical and Biophysical Research Communications

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