TY - JOUR
T1 - Renal Function During Neurolept Anaesthesia
AU - Järnberg, Per‐Olof ‐O
AU - Santesson, Joakim
AU - Eklund, Jan
PY - 1978/4
Y1 - 1978/4
N2 - Renal function and central haemodynamics were studied in eight patients, without known histories of renal or cardiovascular disease, during and immediately after upper abdominal surgery under neurolept anaesthesia. Inulin and PAH clearance, fractional sodium and fractional osmolal excretion decreased, while fractional free water reabsorption increased under anaesthesia. Cardiac output, mean systemic arterial pressure and systemic vascular resistance remained virtually unchanged both per‐ and postoperatively. Renal haemodynamics were promptly restored postoperatively, while fractional sodium and fractional osmolal excretion were unaltered and antidiuresis increased. It is concluded that neurolept anaesthesia, as far as renal function is concerned, is well suited for the anaesthetic management of the poor‐risk patient.
AB - Renal function and central haemodynamics were studied in eight patients, without known histories of renal or cardiovascular disease, during and immediately after upper abdominal surgery under neurolept anaesthesia. Inulin and PAH clearance, fractional sodium and fractional osmolal excretion decreased, while fractional free water reabsorption increased under anaesthesia. Cardiac output, mean systemic arterial pressure and systemic vascular resistance remained virtually unchanged both per‐ and postoperatively. Renal haemodynamics were promptly restored postoperatively, while fractional sodium and fractional osmolal excretion were unaltered and antidiuresis increased. It is concluded that neurolept anaesthesia, as far as renal function is concerned, is well suited for the anaesthetic management of the poor‐risk patient.
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U2 - 10.1111/j.1399-6576.1978.tb01294.x
DO - 10.1111/j.1399-6576.1978.tb01294.x
M3 - Article
C2 - 654856
AN - SCOPUS:0017811124
SN - 0001-5172
VL - 22
SP - 167
EP - 172
JO - Acta Anaesthesiologica Scandinavica
JF - Acta Anaesthesiologica Scandinavica
IS - 2
ER -