Renal function and fluoride formation and excretion during enflurane anaesthesia

Per-Olof Järnberg, J. Ekstrand, L. Irestedt, J. Santesson

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Central circulation, and fluoride formation and excretion were studied in nine patients during enflurane anaesthesia and surgery. Cardiac output and mean systemic arterial pressure remained unchanged compared with preoperative control values. During anaesthesia and surgery, urine flow rate, inulin clearance, PAH clearance and fractional sodium excretion were 60, 65, 55, and 45% of control values, respectively. Mean peak plasma level of fluoride was 20.0 μM. It was reached 4 hours after termination of anaesthesia. Fluoride clearance (C(F) decreased from 23.9 ml X min-1 during anaesthesia. Postoperatively, C(F) increased to 41.6 and 76.0 ml X min-1, respectively, during two consecutive measurement periods. There was no correlation between plasma fluoride levels and depression of any renal function variable.

Original languageEnglish (US)
Pages (from-to)444-452
Number of pages9
JournalActa Anaesthesiologica Scandinavica
Volume23
Issue number5
StatePublished - 1979
Externally publishedYes

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Enflurane
Fluorides
Anesthesia
Kidney
Inulin
Cardiac Output
Arterial Pressure
Sodium
Urine

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

Järnberg, P-O., Ekstrand, J., Irestedt, L., & Santesson, J. (1979). Renal function and fluoride formation and excretion during enflurane anaesthesia. Acta Anaesthesiologica Scandinavica, 23(5), 444-452.

Renal function and fluoride formation and excretion during enflurane anaesthesia. / Järnberg, Per-Olof; Ekstrand, J.; Irestedt, L.; Santesson, J.

In: Acta Anaesthesiologica Scandinavica, Vol. 23, No. 5, 1979, p. 444-452.

Research output: Contribution to journalArticle

Järnberg, P-O, Ekstrand, J, Irestedt, L & Santesson, J 1979, 'Renal function and fluoride formation and excretion during enflurane anaesthesia', Acta Anaesthesiologica Scandinavica, vol. 23, no. 5, pp. 444-452.
Järnberg, Per-Olof ; Ekstrand, J. ; Irestedt, L. ; Santesson, J. / Renal function and fluoride formation and excretion during enflurane anaesthesia. In: Acta Anaesthesiologica Scandinavica. 1979 ; Vol. 23, No. 5. pp. 444-452.
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