Renal Fluoride Excretion During and After Enflurane Anaesthesia: Dependency on Spontaneous Urinary pH‐Variations

P. O. Järnberg, J. Ekstrand, L. Irestedt, J. Santesson

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Renal function, fluoride formation and excretion were studied in seven patients during and after enflurane anaesthesia and surgery. The mean maximal plasma level of fluoride was 17.4 pM. It was reached 2 h after termination of anaesthesia. Pre‐operatively, fractional fluoride clearance (CF/CIn) was 0.31. During anaesthesia and surgery it decreased to 0.10 and postoperatively rose to 0.55 and 0.77 during two consecutive measurement periods. There was a highly significant correlation (P<0.001) between this increase in CF/CIn and the simultaneous rise in urinary pH between the two periods (r=0.91).

Original languageEnglish (US)
Pages (from-to)129-134
Number of pages6
JournalActa Anaesthesiologica Scandinavica
Volume24
Issue number2
DOIs
StatePublished - Apr 1980

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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