Renal fluoride excretion during and after enflurane anaesthesia: Dependency on spontaneous urinary pH-variations

Per-Olof Järnberg, J. Ekstrand, L. Irestedt, J. Santesson

Research output: Contribution to journalArticle

13 Scopus citations


Recent function, fluoride formation and excretion were studied in 7 patients during and after enflurane anesthesia and surgery. The mean maximal plasma level of fluoride was 17.4 μM. It was reached 2 hr after termination of anesthesia. Pre-operatively, fractional fluoride clearance (CF/CIn) was 0.31. During anesthesia and surgery it decreased to 0.10 and postoperatively rose to 0.55 and 0.77 during 2 consecutive measurement periods. There was a highly significant correlation (P <0.001) between this increase in CF/CIn and the simultaneous rise in urinary pH between the 2 periods (r = 0.91).

Original languageEnglish (US)
Pages (from-to)129-134
Number of pages6
JournalActa Anaesthesiologica Scandinavica
Issue number2
Publication statusPublished - 1980
Externally publishedYes


ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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