Renal excretion of fluoride during water diuresis and induced urinary ph-changes in man

P. O. Järnberg; J. Ekstrand; M. Ehrnebo

doi:10.1016/0378-4274(83)90084-X

Renal excretion of fluoride during water diuresis and induced urinary ph-changes in man

P. O. Järnberg, J. Ekstrand, M. Ehrnebo

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Abstract

Fluoride renal clearance (C_F) was studied in young healthy subjects with standard clearance technique following administration of 3 mg F as a 30-min constant infusion. High urinary flow rates were induced and experiments were performed under both urinary alkaline and acidic conditions. The data showed that a high urinary flow resulted in maximum fluoride clearance. High water diuresis may therefore be an important part in the treatment of acute fluoride intoxication.

Original language	English (US)
Pages (from-to)	141-146
Number of pages	6
Journal	Toxicology Letters
Volume	18
Issue number	1-2
DOIs	https://doi.org/10.1016/0378-4274(83)90084-X
State	Published - Aug 1983
Externally published	Yes

ASJC Scopus subject areas

Toxicology

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10.1016/0378-4274(83)90084-X

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title = "Renal excretion of fluoride during water diuresis and induced urinary ph-changes in man",

abstract = "Fluoride renal clearance (CF) was studied in young healthy subjects with standard clearance technique following administration of 3 mg F as a 30-min constant infusion. High urinary flow rates were induced and experiments were performed under both urinary alkaline and acidic conditions. The data showed that a high urinary flow resulted in maximum fluoride clearance. High water diuresis may therefore be an important part in the treatment of acute fluoride intoxication.",

author = "J{\"a}rnberg, {P. O.} and J. Ekstrand and M. Ehrnebo",

note = "Funding Information: This investigationw as supportedb y grants from the Tore Nilson Fund, The SwedishP atent RevenueR esearchF und and The SwedishM edical ResearchC oun-cil, project No. 6002.",

year = "1983",

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doi = "10.1016/0378-4274(83)90084-X",

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AU - Järnberg, P. O.

AU - Ekstrand, J.

AU - Ehrnebo, M.

N1 - Funding Information: This investigationw as supportedb y grants from the Tore Nilson Fund, The SwedishP atent RevenueR esearchF und and The SwedishM edical ResearchC oun-cil, project No. 6002.

PY - 1983/8

Y1 - 1983/8

N2 - Fluoride renal clearance (CF) was studied in young healthy subjects with standard clearance technique following administration of 3 mg F as a 30-min constant infusion. High urinary flow rates were induced and experiments were performed under both urinary alkaline and acidic conditions. The data showed that a high urinary flow resulted in maximum fluoride clearance. High water diuresis may therefore be an important part in the treatment of acute fluoride intoxication.

AB - Fluoride renal clearance (CF) was studied in young healthy subjects with standard clearance technique following administration of 3 mg F as a 30-min constant infusion. High urinary flow rates were induced and experiments were performed under both urinary alkaline and acidic conditions. The data showed that a high urinary flow resulted in maximum fluoride clearance. High water diuresis may therefore be an important part in the treatment of acute fluoride intoxication.

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JO - Toxicology Letters

JF - Toxicology Letters

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ER -

Renal excretion of fluoride during water diuresis and induced urinary ph-changes in man

Abstract

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