Renal excretion of fluoride during water diuresis and induced urinary ph-changes in man

Per-Olof Järnberg, J. Ekstrand, M. Ehrnebo

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Fluoride renal clearance (CF) was studied in young healthy subjects with standard clearance technique following administration of 3 mg F as a 30-min constant infusion. High urinary flow rates were induced and experiments were performed under both urinary alkaline and acidic conditions. The data showed that a high urinary flow resulted in maximum fluoride clearance. High water diuresis may therefore be an important part in the treatment of acute fluoride intoxication.

Original languageEnglish (US)
Pages (from-to)141-146
Number of pages6
JournalToxicology Letters
Volume18
Issue number1-2
DOIs
StatePublished - 1983
Externally publishedYes

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Diuresis
Fluorides
Water
Healthy Volunteers
Flow rate
Kidney
Renal Elimination
Experiments
Therapeutics

ASJC Scopus subject areas

  • Toxicology

Cite this

Renal excretion of fluoride during water diuresis and induced urinary ph-changes in man. / Järnberg, Per-Olof; Ekstrand, J.; Ehrnebo, M.

In: Toxicology Letters, Vol. 18, No. 1-2, 1983, p. 141-146.

Research output: Contribution to journalArticle

Järnberg, Per-Olof ; Ekstrand, J. ; Ehrnebo, M. / Renal excretion of fluoride during water diuresis and induced urinary ph-changes in man. In: Toxicology Letters. 1983 ; Vol. 18, No. 1-2. pp. 141-146.
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