Remodelling of neuromuscular systems during insect metamorphosis

Karla Kent, Christos Consoulas, Karen Duncan, Rebecca M. Johnston, Rene Luedeman, Richard B. Levine

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

During metamorphosis in the hawkmoth, Manduca sexta, the larval thoracic legs are replaced by a new set of adult legs that include new sensory neurons and muscles, and participate in new patterns of locomotor activity. Larval leg motoneurons persist to innervate the new adult leg muscles, but undergo striking changes in dendritic morphology that are regulated by the insect steroid, 20-hydroxyecdysone. In the periphery, the motor terminals regress as larval muscles degenerate, and expand as new adult muscles form from myoblasts. Evidence obtained both in vivo and in vitro suggests that the proliferation of myoblasts during metamorphosis is dependent upon innervation.

Original languageEnglish (US)
Pages (from-to)578-584
Number of pages7
JournalIntegrative and Comparative Biology
Volume35
Issue number6
DOIs
StatePublished - Dec 1995

Fingerprint

Remodeling
insects
muscles
Muscle
metamorphosis
Insects
Leg
legs
Muscles
myoblasts
Myoblasts
Ecdysterone
Manduca
proliferation
steroids
Steroids
ecdysterone
sensory neurons
Manduca sexta
Motor Neurons

ASJC Scopus subject areas

  • Molecular Biology
  • Statistics and Probability
  • Computational Mathematics
  • Condensed Matter Physics
  • Social Sciences(all)
  • Plant Science
  • Animal Science and Zoology

Cite this

Kent, K., Consoulas, C., Duncan, K., Johnston, R. M., Luedeman, R., & Levine, R. B. (1995). Remodelling of neuromuscular systems during insect metamorphosis. Integrative and Comparative Biology, 35(6), 578-584. https://doi.org/10.1093/icb/35.6.578

Remodelling of neuromuscular systems during insect metamorphosis. / Kent, Karla; Consoulas, Christos; Duncan, Karen; Johnston, Rebecca M.; Luedeman, Rene; Levine, Richard B.

In: Integrative and Comparative Biology, Vol. 35, No. 6, 12.1995, p. 578-584.

Research output: Contribution to journalArticle

Kent, K, Consoulas, C, Duncan, K, Johnston, RM, Luedeman, R & Levine, RB 1995, 'Remodelling of neuromuscular systems during insect metamorphosis', Integrative and Comparative Biology, vol. 35, no. 6, pp. 578-584. https://doi.org/10.1093/icb/35.6.578
Kent, Karla ; Consoulas, Christos ; Duncan, Karen ; Johnston, Rebecca M. ; Luedeman, Rene ; Levine, Richard B. / Remodelling of neuromuscular systems during insect metamorphosis. In: Integrative and Comparative Biology. 1995 ; Vol. 35, No. 6. pp. 578-584.
@article{79976dd3d49945e1bf9584311cf3d0e5,
title = "Remodelling of neuromuscular systems during insect metamorphosis",
abstract = "During metamorphosis in the hawkmoth, Manduca sexta, the larval thoracic legs are replaced by a new set of adult legs that include new sensory neurons and muscles, and participate in new patterns of locomotor activity. Larval leg motoneurons persist to innervate the new adult leg muscles, but undergo striking changes in dendritic morphology that are regulated by the insect steroid, 20-hydroxyecdysone. In the periphery, the motor terminals regress as larval muscles degenerate, and expand as new adult muscles form from myoblasts. Evidence obtained both in vivo and in vitro suggests that the proliferation of myoblasts during metamorphosis is dependent upon innervation.",
author = "Karla Kent and Christos Consoulas and Karen Duncan and Johnston, {Rebecca M.} and Rene Luedeman and Levine, {Richard B.}",
year = "1995",
month = "12",
doi = "10.1093/icb/35.6.578",
language = "English (US)",
volume = "35",
pages = "578--584",
journal = "Integrative and Comparative Biology",
issn = "1540-7063",
publisher = "Oxford University Press",
number = "6",

}

TY - JOUR

T1 - Remodelling of neuromuscular systems during insect metamorphosis

AU - Kent, Karla

AU - Consoulas, Christos

AU - Duncan, Karen

AU - Johnston, Rebecca M.

AU - Luedeman, Rene

AU - Levine, Richard B.

PY - 1995/12

Y1 - 1995/12

N2 - During metamorphosis in the hawkmoth, Manduca sexta, the larval thoracic legs are replaced by a new set of adult legs that include new sensory neurons and muscles, and participate in new patterns of locomotor activity. Larval leg motoneurons persist to innervate the new adult leg muscles, but undergo striking changes in dendritic morphology that are regulated by the insect steroid, 20-hydroxyecdysone. In the periphery, the motor terminals regress as larval muscles degenerate, and expand as new adult muscles form from myoblasts. Evidence obtained both in vivo and in vitro suggests that the proliferation of myoblasts during metamorphosis is dependent upon innervation.

AB - During metamorphosis in the hawkmoth, Manduca sexta, the larval thoracic legs are replaced by a new set of adult legs that include new sensory neurons and muscles, and participate in new patterns of locomotor activity. Larval leg motoneurons persist to innervate the new adult leg muscles, but undergo striking changes in dendritic morphology that are regulated by the insect steroid, 20-hydroxyecdysone. In the periphery, the motor terminals regress as larval muscles degenerate, and expand as new adult muscles form from myoblasts. Evidence obtained both in vivo and in vitro suggests that the proliferation of myoblasts during metamorphosis is dependent upon innervation.

UR - http://www.scopus.com/inward/record.url?scp=77957217073&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77957217073&partnerID=8YFLogxK

U2 - 10.1093/icb/35.6.578

DO - 10.1093/icb/35.6.578

M3 - Article

AN - SCOPUS:77957217073

VL - 35

SP - 578

EP - 584

JO - Integrative and Comparative Biology

JF - Integrative and Comparative Biology

SN - 1540-7063

IS - 6

ER -