Relationship of age, gender, race, and body size to infrarenal aortic diameter

F. A. Lederle, G. R. Johnson, S. E. Wilson, I. L. Gordon, E. P. Chute, F. N. Littooy, W. C. Krupski, D. Bandyk, G. W. Barone, L. M. Graham, R. J. Hye, D. B. Reinke, L. M. Messina, C. W. Acher, D. J. Ballard, H. J. Ansel, A. W. Averbook, M. S. Makaroun, G. L. Moneta, J. FreischlagR. G. Makhoul, M. Tabbara, G. B. Zelenock, J. H. Rapp

    Research output: Contribution to journalArticle

    163 Scopus citations

    Abstract

    Purpose: To assess the effects of age, gender, race, and body size on infrarenal aortic diameter (IAD) and to determine expected values for IAD on the basis of these factors. Method: Veterans aged 50 to 79 years at 15 Department of Veterans Affairs medical centers were invited to undergo ultrasound measurement of IAD and complete a prescreening questionnaire. We report here on 69,905 subjects who had no previous history of abdominal aortic aneurysm (AAA) and no ultrasound evidence of AAA (defined as IAD ≤ 3.0 cm). Results: Although age, gender, black race, height, weight, body mass index, and body surface area were associated with IAD by multivariate linear regression (all p < 0.001), the effects were small. Female sex was associated with a 0.14 cm reduction in IAD and black race with a 0.01 cm increase in IAD. A 0.1 cm change in IAD was associated with large changes in the independent variables: 29 years in age, 19 cm or 40 cm in height, 35 kg in weight, 11 kg/m2 in body mass index, and 0.35 m2 in body surface area. Nearly all height-weight groups were within 0.1 cm of the gender means, and the unadjusted gender means differed by only 0.23 cm. The variation among medical centers had more influence on IAD than did the combination of ages gender, race, and body size. Conclusions: Age, gender, race, and body size have statistically significant but small effects on IAD. Use of these parameters to define AAA may not offer sufficient advantage over simpler definitions (such as an IAD ≤23.0 cm) to be warranted.

    Original languageEnglish (US)
    Pages (from-to)595-601
    Number of pages7
    JournalJournal of vascular surgery
    Volume26
    Issue number4
    DOIs
    StatePublished - Jan 1 1997

    ASJC Scopus subject areas

    • Surgery
    • Cardiology and Cardiovascular Medicine

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    Lederle, F. A., Johnson, G. R., Wilson, S. E., Gordon, I. L., Chute, E. P., Littooy, F. N., Krupski, W. C., Bandyk, D., Barone, G. W., Graham, L. M., Hye, R. J., Reinke, D. B., Messina, L. M., Acher, C. W., Ballard, D. J., Ansel, H. J., Averbook, A. W., Makaroun, M. S., Moneta, G. L., ... Rapp, J. H. (1997). Relationship of age, gender, race, and body size to infrarenal aortic diameter. Journal of vascular surgery, 26(4), 595-601. https://doi.org/10.1016/S0741-5214(97)70057-0