Relationship between concussion and neuropsychological performance in college football players

Michael W. Collins, Scott H. Grindel, Mark R. Lovell, Duane E. Dede, David J. Moser, Benjamin R. Phalin, Sally Nogle, Michael Wasik, David Cordry, Michelle Klotz Daugherty, Samuel F. Sears, Guy Nicolette, Peter Indelicato, Douglas McKeag

Research output: Contribution to journalArticle

566 Citations (Scopus)

Abstract

Context: Despite the high prevalence and potentially serious outcomes associated with concussion in athletes, there is little systematic research examining risk factors and short- and long-term outcomes. Objectives: To assess the relationship between concussion history and learning disability (LD) and the association of these variables with neuropsychological performance and to evaluate postconcussion recovery in a sample of college football prayers. Design, Setting, and Participants: A total of 393 athletes from 4 university football programs across the United States received preseason baseline evaluations between May 1997 and February 1999. Subjects who had subsequent football-related acute concussions (n = 16) underwent neuropsychological comparison with matched control athletes from within the sample (n = 10). Main Outcome Measures: Clinical interview, 8 neuropsychological measures, and concussion symptom scale ratings at baseline and after concussion. Results: Of the 393 players, 129 (34%) had experienced 1 previous concussion and 79 (20%) had experienced 2 or more concussions. Multivariate analysis of variance yielded significant main effects for both LD (P<.001) and concussion history (P = .009), resulting in lowered baseline neuropsychological performance. A significant interaction was found between LD and history of multiple concussions and LD on 2 neuropsychological measures (Trail-Making Test, Form B [P=.007] and Symbol Digit Modalities Test [P = .009]), indicating poorer performance for the group with LD and multiple concussions compared with other groups. A discriminant function analysis using neuropsychological testing of athletes 24 hours after acute in-season concussion compared with controls resulted in an overall 89.5% correct classification rate. Conclusions: Our study suggests that neuropsychological assessment is a useful indicator of cognitive functioning in athletes and that both history of multiple concussions and LD are associated with reduced cognitive performance. These variables may be detrimentally synergistic and should receive further study.

Original languageEnglish (US)
Pages (from-to)964-970
Number of pages7
JournalJournal of the American Medical Association
Volume282
Issue number10
DOIs
StatePublished - Sep 8 1999
Externally publishedYes

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Football
Learning Disorders
Athletes
History
Trail Making Test
Religion
Discriminant Analysis
Analysis of Variance
Multivariate Analysis
Outcome Assessment (Health Care)
Interviews
Research

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Relationship between concussion and neuropsychological performance in college football players. / Collins, Michael W.; Grindel, Scott H.; Lovell, Mark R.; Dede, Duane E.; Moser, David J.; Phalin, Benjamin R.; Nogle, Sally; Wasik, Michael; Cordry, David; Daugherty, Michelle Klotz; Sears, Samuel F.; Nicolette, Guy; Indelicato, Peter; McKeag, Douglas.

In: Journal of the American Medical Association, Vol. 282, No. 10, 08.09.1999, p. 964-970.

Research output: Contribution to journalArticle

Collins, MW, Grindel, SH, Lovell, MR, Dede, DE, Moser, DJ, Phalin, BR, Nogle, S, Wasik, M, Cordry, D, Daugherty, MK, Sears, SF, Nicolette, G, Indelicato, P & McKeag, D 1999, 'Relationship between concussion and neuropsychological performance in college football players', Journal of the American Medical Association, vol. 282, no. 10, pp. 964-970. https://doi.org/10.1001/jama.282.10.964
Collins, Michael W. ; Grindel, Scott H. ; Lovell, Mark R. ; Dede, Duane E. ; Moser, David J. ; Phalin, Benjamin R. ; Nogle, Sally ; Wasik, Michael ; Cordry, David ; Daugherty, Michelle Klotz ; Sears, Samuel F. ; Nicolette, Guy ; Indelicato, Peter ; McKeag, Douglas. / Relationship between concussion and neuropsychological performance in college football players. In: Journal of the American Medical Association. 1999 ; Vol. 282, No. 10. pp. 964-970.
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AU - Lovell, Mark R.

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AU - Moser, David J.

AU - Phalin, Benjamin R.

AU - Nogle, Sally

AU - Wasik, Michael

AU - Cordry, David

AU - Daugherty, Michelle Klotz

AU - Sears, Samuel F.

AU - Nicolette, Guy

AU - Indelicato, Peter

AU - McKeag, Douglas

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