Abstract
This review will present a current understanding of mechanisms for the initiation of base excision repair (BER) of oxidatively-induced DNA damage and the biological consequences of deficiencies in these enzymes in mouse model systems and human populations.
Original language | English (US) |
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Pages (from-to) | 460-478 |
Number of pages | 19 |
Journal | Free Radical Research |
Volume | 46 |
Issue number | 4 |
DOIs | |
State | Published - Apr 2012 |
Keywords
- Glycosylase-deficient mice
- MUTYH
- Metabolic disease
- NEIL1,2,3
- NTH1
- OGG1
ASJC Scopus subject areas
- Biochemistry