Regulation of DNA glycosylases and their role in limiting disease

Research output: Contribution to journalReview article

28 Scopus citations

Abstract

This review will present a current understanding of mechanisms for the initiation of base excision repair (BER) of oxidatively-induced DNA damage and the biological consequences of deficiencies in these enzymes in mouse model systems and human populations.

Original languageEnglish (US)
Pages (from-to)460-478
Number of pages19
JournalFree Radical Research
Volume46
Issue number4
DOIs
StatePublished - Apr 2012

Keywords

  • Glycosylase-deficient mice
  • MUTYH
  • Metabolic disease
  • NEIL1,2,3
  • NTH1
  • OGG1

ASJC Scopus subject areas

  • Biochemistry

Fingerprint Dive into the research topics of 'Regulation of DNA glycosylases and their role in limiting disease'. Together they form a unique fingerprint.

  • Cite this