Regional distribution of glutamate receptor mRNA in the monkey hippocampus and temporal cortex: Influence of estradiol

Steven G. Kohama, Vasilios T. Garyfallou, Henryk F. Urbanski

    Research output: Contribution to journalArticle

    10 Scopus citations

    Abstract

    The distribution of N-methyl-D-aspartate (NMDA) and α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) glutamate receptor subunits was examined in the hippocampus and temporal cortex of adult ovariectomized female rhesus macaques, some of which received estradiol replacement. In situ hybridization revealed a generalized overlap of NR1, GluR1, and GluR2 subunit mRNAs, but no effect due to estradiol treatment. However, regional differences in expression were noted for each subunit.

    Original languageEnglish (US)
    Pages (from-to)328-332
    Number of pages5
    JournalMolecular Brain Research
    Volume53
    Issue number1-2
    DOIs
    StatePublished - Jan 1 1998

    Keywords

    • AMPA
    • In situ hybridization
    • NMDA

    ASJC Scopus subject areas

    • Molecular Biology
    • Cellular and Molecular Neuroscience

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