Abstract
The distribution of N-methyl-D-aspartate (NMDA) and α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) glutamate receptor subunits was examined in the hippocampus and temporal cortex of adult ovariectomized female rhesus macaques, some of which received estradiol replacement. In situ hybridization revealed a generalized overlap of NR1, GluR1, and GluR2 subunit mRNAs, but no effect due to estradiol treatment. However, regional differences in expression were noted for each subunit.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 328-332 |
| Number of pages | 5 |
| Journal | Molecular Brain Research |
| Volume | 53 |
| Issue number | 1-2 |
| DOIs | |
| State | Published - Jan 1998 |
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Keywords
- AMPA
- In situ hybridization
- NMDA
ASJC Scopus subject areas
- Molecular Biology
- Cellular and Molecular Neuroscience
Cite this
Regional distribution of glutamate receptor mRNA in the monkey hippocampus and temporal cortex : Influence of estradiol. / Kohama, Steven; Garyfallou, Vasilios T.; Urbanski, Henryk.
In: Molecular Brain Research, Vol. 53, No. 1-2, 01.1998, p. 328-332.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Regional distribution of glutamate receptor mRNA in the monkey hippocampus and temporal cortex
T2 - Influence of estradiol
AU - Kohama, Steven
AU - Garyfallou, Vasilios T.
AU - Urbanski, Henryk
PY - 1998/1
Y1 - 1998/1
N2 - The distribution of N-methyl-D-aspartate (NMDA) and α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) glutamate receptor subunits was examined in the hippocampus and temporal cortex of adult ovariectomized female rhesus macaques, some of which received estradiol replacement. In situ hybridization revealed a generalized overlap of NR1, GluR1, and GluR2 subunit mRNAs, but no effect due to estradiol treatment. However, regional differences in expression were noted for each subunit.
AB - The distribution of N-methyl-D-aspartate (NMDA) and α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) glutamate receptor subunits was examined in the hippocampus and temporal cortex of adult ovariectomized female rhesus macaques, some of which received estradiol replacement. In situ hybridization revealed a generalized overlap of NR1, GluR1, and GluR2 subunit mRNAs, but no effect due to estradiol treatment. However, regional differences in expression were noted for each subunit.
KW - AMPA
KW - In situ hybridization
KW - NMDA
UR - http://www.scopus.com/inward/record.url?scp=0031932592&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031932592&partnerID=8YFLogxK
U2 - 10.1016/S0169-328X(97)00282-9
DO - 10.1016/S0169-328X(97)00282-9
M3 - Article
C2 - 9473714
AN - SCOPUS:0031932592
VL - 53
SP - 328
EP - 332
JO - Brain Research
JF - Brain Research
SN - 0006-8993
IS - 1-2
ER -