Abstract
Silent thyroiditis, excluding postpartum thyroiditis and destructive amiodarone thyroiditis, is a relatively uncommon cause of thyrotoxicosis and recurrent cases are even rarer. We present four patients with recurrent silent thyroiditis. The number of episodes ranged from two to nine. All four patients had episodes that were similar in duration (4-6 weeks) as well as in their clinical (no viral prodrome or neck pain), biochemical (high total triiodothyronine [T3], free thyroxine [T4], and low thyrotropin [TSH] presence of antibodies to thyroid antigens), and scintigraphic (low radioiodine uptake) findings. Individual symptoms and symptom-free duration (from 1 to 4 years) were more variable. No associations were found with regard to medications, pregnancies, or other disease states previously implicated in thyroiditis. One patient was unsuccessfully prescribed thyroid hormone to prevent recurrence. Three were treated with radioablative iodine therapy during the recovery phase of an episode; they became hypothyroid and take replacement L-thyroxine. They have remained symptom free.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 671-675 |
| Number of pages | 5 |
| Journal | Thyroid |
| Volume | 17 |
| Issue number | 7 |
| DOIs | |
| State | Published - Jul 1 2007 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Endocrinology
Cite this
Recurrent silent thyroiditis : A report of four patients and review of the literature. / Mittra, Erik; McDougall, I. Ross.
In: Thyroid, Vol. 17, No. 7, 01.07.2007, p. 671-675.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Recurrent silent thyroiditis
T2 - A report of four patients and review of the literature
AU - Mittra, Erik
AU - McDougall, I. Ross
PY - 2007/7/1
Y1 - 2007/7/1
N2 - Silent thyroiditis, excluding postpartum thyroiditis and destructive amiodarone thyroiditis, is a relatively uncommon cause of thyrotoxicosis and recurrent cases are even rarer. We present four patients with recurrent silent thyroiditis. The number of episodes ranged from two to nine. All four patients had episodes that were similar in duration (4-6 weeks) as well as in their clinical (no viral prodrome or neck pain), biochemical (high total triiodothyronine [T3], free thyroxine [T4], and low thyrotropin [TSH] presence of antibodies to thyroid antigens), and scintigraphic (low radioiodine uptake) findings. Individual symptoms and symptom-free duration (from 1 to 4 years) were more variable. No associations were found with regard to medications, pregnancies, or other disease states previously implicated in thyroiditis. One patient was unsuccessfully prescribed thyroid hormone to prevent recurrence. Three were treated with radioablative iodine therapy during the recovery phase of an episode; they became hypothyroid and take replacement L-thyroxine. They have remained symptom free.
AB - Silent thyroiditis, excluding postpartum thyroiditis and destructive amiodarone thyroiditis, is a relatively uncommon cause of thyrotoxicosis and recurrent cases are even rarer. We present four patients with recurrent silent thyroiditis. The number of episodes ranged from two to nine. All four patients had episodes that were similar in duration (4-6 weeks) as well as in their clinical (no viral prodrome or neck pain), biochemical (high total triiodothyronine [T3], free thyroxine [T4], and low thyrotropin [TSH] presence of antibodies to thyroid antigens), and scintigraphic (low radioiodine uptake) findings. Individual symptoms and symptom-free duration (from 1 to 4 years) were more variable. No associations were found with regard to medications, pregnancies, or other disease states previously implicated in thyroiditis. One patient was unsuccessfully prescribed thyroid hormone to prevent recurrence. Three were treated with radioablative iodine therapy during the recovery phase of an episode; they became hypothyroid and take replacement L-thyroxine. They have remained symptom free.
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UR - http://www.scopus.com/inward/citedby.url?scp=34548165711&partnerID=8YFLogxK
U2 - 10.1089/thy.2006.0335
DO - 10.1089/thy.2006.0335
M3 - Article
C2 - 17696838
AN - SCOPUS:34548165711
VL - 17
SP - 671
EP - 675
JO - Thyroid
JF - Thyroid
SN - 1050-7256
IS - 7
ER -