Recurrent medulloblastoma: Frequency of tumor enhancement on Gd-DTPA MR imaging

N. Rollins, D. Mendelsohn, A. Mulne, Robert Barton, J. Diehl, N. Reyes, F. Sklar

Research output: Contribution to journalArticle

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Abstract

Thirty-two children with medulloblastoma were evaluated postoperatively with conventional and gadolinium-enhanced MR imaging. Eleven patients had abnormal cranial MR studies; nine of these had recurrent tumor. In six patients recurrent tumor enhanced with Gd, while in the other three patients recurrent tumor did not enhance. The remaining two patients had areas of abnormal Gd enhancement that were caused by radiation-induced breakdown of the blood-brain barrier rather than by recurrent tumor. This study shows that not all recurrent medulloblastoma enhances and that the absence of Gd enhancement does not necessarily indicate the absence of recurrent tumor.

Original languageEnglish (US)
Pages (from-to)583-587
Number of pages5
JournalAmerican Journal of Neuroradiology
Volume11
Issue number3
StatePublished - 1990
Externally publishedYes

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Gadolinium DTPA
Medulloblastoma
Neoplasms
Gadolinium
Blood-Brain Barrier
Radiation

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Rollins, N., Mendelsohn, D., Mulne, A., Barton, R., Diehl, J., Reyes, N., & Sklar, F. (1990). Recurrent medulloblastoma: Frequency of tumor enhancement on Gd-DTPA MR imaging. American Journal of Neuroradiology, 11(3), 583-587.

Recurrent medulloblastoma : Frequency of tumor enhancement on Gd-DTPA MR imaging. / Rollins, N.; Mendelsohn, D.; Mulne, A.; Barton, Robert; Diehl, J.; Reyes, N.; Sklar, F.

In: American Journal of Neuroradiology, Vol. 11, No. 3, 1990, p. 583-587.

Research output: Contribution to journalArticle

Rollins, N, Mendelsohn, D, Mulne, A, Barton, R, Diehl, J, Reyes, N & Sklar, F 1990, 'Recurrent medulloblastoma: Frequency of tumor enhancement on Gd-DTPA MR imaging', American Journal of Neuroradiology, vol. 11, no. 3, pp. 583-587.
Rollins, N. ; Mendelsohn, D. ; Mulne, A. ; Barton, Robert ; Diehl, J. ; Reyes, N. ; Sklar, F. / Recurrent medulloblastoma : Frequency of tumor enhancement on Gd-DTPA MR imaging. In: American Journal of Neuroradiology. 1990 ; Vol. 11, No. 3. pp. 583-587.
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