Recombinant human erythropoietin for a Jehovah's witness with anemia of thermal injury

Lynn K. Boshkov, Edward E. Tredget, Anna Janowska‐Wieczorek

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

We report the use of recombinant human erythropoietin (rh‐Ep) as an alternative to transfusion therapy in a burn victim who was a Jehovah's Witness and refused blood transfusion. Despite endogenous elevated erythropoietin levels, the patient was reticulocytopenic and administration of rh‐Ep was accompanied by a 10‐fold increase in reticulocyte response and a rise in hemoglobin from 7.4 to 10.4 g/dl over a 12‐day period. We suggest that the exogenously administered erythropoietin overcame a clinically inadequate endogenous erythropoietin response.

Original languageEnglish (US)
Pages (from-to)53-54
Number of pages2
JournalAmerican Journal of Hematology
Volume37
Issue number1
DOIs
StatePublished - May 1991

Keywords

  • anemia
  • burns
  • recombinant human erythropoietin (rh‐Ep)

ASJC Scopus subject areas

  • Hematology

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