Recent advances in systemic acquired resistance research - A review

Michelle D. Hunt, Urs H. Neuenschwander, Terrence P. Delaney, Kristianna Weymann, Leslie B. Friedrich, Kay A. Lawton, Henry York Steiner, John A. Ryals

Research output: Contribution to journalReview article

70 Citations (Scopus)

Abstract

Little is known about the signal transduction events that lead to the establishment of the broad-spectrum, inducible plant immunity called systemic acquired resistance (SAR). Salicylic acid (SA) accumulation has been shown to be essential for the expression of SAR and plays a key role in SAR signaling. Hydrogen peroxide has been proposed to serve as a second messenger of SA. However, our results do not support such a role in the establishment of SAR. Further elucidation of SAR signal transduction has been facilitated by the identification and characterization of mutants. The lesions simulating disease (lsd) resistance response mutant class exhibits spontaneous lesions similar to those that occur during the hypersensitive response. Interestingly, some lsd mutants lose their lesioned phenotype when SA accumulation is prevented by expression of the nahG gene (encoding salicylate hydroxylase), thereby providing evidence for a feedback loop in SAR signal transduction. Characterization of a mutant non-responsive to SAR activator treatments has provided additional evidence for common signaling components between SAR and gene-for-gene resistance.

Original languageEnglish (US)
Pages (from-to)89-95
Number of pages7
JournalGene
Volume179
Issue number1
DOIs
StatePublished - Nov 7 1996
Externally publishedYes

Fingerprint

Salicylic Acid
Signal Transduction
salicylate 1-monooxygenase
Plant Immunity
Research
Disease Resistance
Second Messenger Systems
Hydrogen Peroxide
Genes
Phenotype
Gene Expression

Keywords

  • Cell death
  • Disease resistance
  • Hydrogen peroxide
  • Lesions simulating disease
  • Mutant
  • Pathogenesis-related protein
  • Salicylic acid
  • Signal transduction

ASJC Scopus subject areas

  • Medicine(all)
  • Genetics

Cite this

Hunt, M. D., Neuenschwander, U. H., Delaney, T. P., Weymann, K., Friedrich, L. B., Lawton, K. A., ... Ryals, J. A. (1996). Recent advances in systemic acquired resistance research - A review. Gene, 179(1), 89-95. https://doi.org/10.1016/S0378-1119(96)00429-5

Recent advances in systemic acquired resistance research - A review. / Hunt, Michelle D.; Neuenschwander, Urs H.; Delaney, Terrence P.; Weymann, Kristianna; Friedrich, Leslie B.; Lawton, Kay A.; Steiner, Henry York; Ryals, John A.

In: Gene, Vol. 179, No. 1, 07.11.1996, p. 89-95.

Research output: Contribution to journalReview article

Hunt, MD, Neuenschwander, UH, Delaney, TP, Weymann, K, Friedrich, LB, Lawton, KA, Steiner, HY & Ryals, JA 1996, 'Recent advances in systemic acquired resistance research - A review', Gene, vol. 179, no. 1, pp. 89-95. https://doi.org/10.1016/S0378-1119(96)00429-5
Hunt MD, Neuenschwander UH, Delaney TP, Weymann K, Friedrich LB, Lawton KA et al. Recent advances in systemic acquired resistance research - A review. Gene. 1996 Nov 7;179(1):89-95. https://doi.org/10.1016/S0378-1119(96)00429-5
Hunt, Michelle D. ; Neuenschwander, Urs H. ; Delaney, Terrence P. ; Weymann, Kristianna ; Friedrich, Leslie B. ; Lawton, Kay A. ; Steiner, Henry York ; Ryals, John A. / Recent advances in systemic acquired resistance research - A review. In: Gene. 1996 ; Vol. 179, No. 1. pp. 89-95.
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