Realtime adherence monitoring of antiretroviral therapy among HIV-infected adults and children in rural Uganda

Jessica E. Haberer; Julius Kiwanuka; Denis Nansera; Conrad Muzoora; Peter W. Hunt; Jacquelyn So; Michael O'Donnell; Mark Siedner; Jeffrey N. Martin; David R. Bangsberg

doi:10.1097/QAD.0b013e328363b53f

Realtime adherence monitoring of antiretroviral therapy among HIV-infected adults and children in rural Uganda

Jessica E. Haberer, Julius Kiwanuka, Denis Nansera, Conrad Muzoora, Peter W. Hunt, Jacquelyn So, Michael O'Donnell, Mark Siedner, Jeffrey N. Martin, David R. Bangsberg

Research output: Contribution to journal › Article › peer-review

59 Scopus citations

Abstract

A real-time wireless electronic adherence monitor (EAM) and weekly self-report of missed doses via interactive voice response (IVR) and short message service (SMS) queries were used to measure antiretroviral therapy adherence in 49 adults and 46 children in rural Uganda. Median adherence was 89.5% among adults and 92.8% among children by EAM, and 99-100% for both adults and children by IVR/SMS self-report. Loss of viral suppression was significantly associated with adherence by EAM (odds ratio 0.58 for each 10% increase), but not IVR/SMS. Wireless EAM creates an exciting opportunity to monitor and potentially intervene with adherence challenges as they are happening.

Original language	English (US)
Pages (from-to)	2166-2168
Number of pages	3
Journal	AIDS
Volume	27
Issue number	13
DOIs	https://doi.org/10.1097/QAD.0b013e328363b53f
State	Published - Aug 24 2013
Externally published	Yes

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Infectious Diseases

Access to Document

10.1097/QAD.0b013e328363b53f

Cite this

@article{0e93b160f02a415bbed66dad09563c04,

title = "Realtime adherence monitoring of antiretroviral therapy among HIV-infected adults and children in rural Uganda",

abstract = "A real-time wireless electronic adherence monitor (EAM) and weekly self-report of missed doses via interactive voice response (IVR) and short message service (SMS) queries were used to measure antiretroviral therapy adherence in 49 adults and 46 children in rural Uganda. Median adherence was 89.5% among adults and 92.8% among children by EAM, and 99-100% for both adults and children by IVR/SMS self-report. Loss of viral suppression was significantly associated with adherence by EAM (odds ratio 0.58 for each 10% increase), but not IVR/SMS. Wireless EAM creates an exciting opportunity to monitor and potentially intervene with adherence challenges as they are happening.",

author = "Haberer, {Jessica E.} and Julius Kiwanuka and Denis Nansera and Conrad Muzoora and Hunt, {Peter W.} and Jacquelyn So and Michael O'Donnell and Mark Siedner and Martin, {Jeffrey N.} and Bangsberg, {David R.}",

year = "2013",

month = aug,

day = "24",

doi = "10.1097/QAD.0b013e328363b53f",

language = "English (US)",

volume = "27",

pages = "2166--2168",

journal = "AIDS",

issn = "0269-9370",

publisher = "Lippincott Williams and Wilkins",

number = "13",

}

TY - JOUR

T1 - Realtime adherence monitoring of antiretroviral therapy among HIV-infected adults and children in rural Uganda

AU - Haberer, Jessica E.

AU - Kiwanuka, Julius

AU - Nansera, Denis

AU - Muzoora, Conrad

AU - Hunt, Peter W.

AU - So, Jacquelyn

AU - O'Donnell, Michael

AU - Siedner, Mark

AU - Martin, Jeffrey N.

AU - Bangsberg, David R.

PY - 2013/8/24

Y1 - 2013/8/24

N2 - A real-time wireless electronic adherence monitor (EAM) and weekly self-report of missed doses via interactive voice response (IVR) and short message service (SMS) queries were used to measure antiretroviral therapy adherence in 49 adults and 46 children in rural Uganda. Median adherence was 89.5% among adults and 92.8% among children by EAM, and 99-100% for both adults and children by IVR/SMS self-report. Loss of viral suppression was significantly associated with adherence by EAM (odds ratio 0.58 for each 10% increase), but not IVR/SMS. Wireless EAM creates an exciting opportunity to monitor and potentially intervene with adherence challenges as they are happening.

AB - A real-time wireless electronic adherence monitor (EAM) and weekly self-report of missed doses via interactive voice response (IVR) and short message service (SMS) queries were used to measure antiretroviral therapy adherence in 49 adults and 46 children in rural Uganda. Median adherence was 89.5% among adults and 92.8% among children by EAM, and 99-100% for both adults and children by IVR/SMS self-report. Loss of viral suppression was significantly associated with adherence by EAM (odds ratio 0.58 for each 10% increase), but not IVR/SMS. Wireless EAM creates an exciting opportunity to monitor and potentially intervene with adherence challenges as they are happening.

UR - http://www.scopus.com/inward/record.url?scp=84884499092&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84884499092&partnerID=8YFLogxK

U2 - 10.1097/QAD.0b013e328363b53f

DO - 10.1097/QAD.0b013e328363b53f

M3 - Article

C2 - 23751260

AN - SCOPUS:84884499092

SN - 0269-9370

VL - 27

SP - 2166

EP - 2168

JO - AIDS

JF - AIDS

IS - 13

ER -

Realtime adherence monitoring of antiretroviral therapy among HIV-infected adults and children in rural Uganda

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this