Realtime adherence monitoring of antiretroviral therapy among HIV-infected adults and children in rural Uganda

Jessica E. Haberer, Julius Kiwanuka, Denis Nansera, Conrad Muzoora, Peter W. Hunt, Jacquelyn So, Michael O'Donnell, Mark Siedner, Jeffrey N. Martin, David R. Bangsberg

Research output: Contribution to journalArticle

47 Scopus citations

Abstract

A real-time wireless electronic adherence monitor (EAM) and weekly self-report of missed doses via interactive voice response (IVR) and short message service (SMS) queries were used to measure antiretroviral therapy adherence in 49 adults and 46 children in rural Uganda. Median adherence was 89.5% among adults and 92.8% among children by EAM, and 99-100% for both adults and children by IVR/SMS self-report. Loss of viral suppression was significantly associated with adherence by EAM (odds ratio 0.58 for each 10% increase), but not IVR/SMS. Wireless EAM creates an exciting opportunity to monitor and potentially intervene with adherence challenges as they are happening.

Original languageEnglish (US)
Pages (from-to)2166-2168
Number of pages3
JournalAIDS
Volume27
Issue number13
DOIs
StatePublished - Aug 24 2013
Externally publishedYes

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ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases

Cite this

Haberer, J. E., Kiwanuka, J., Nansera, D., Muzoora, C., Hunt, P. W., So, J., O'Donnell, M., Siedner, M., Martin, J. N., & Bangsberg, D. R. (2013). Realtime adherence monitoring of antiretroviral therapy among HIV-infected adults and children in rural Uganda. AIDS, 27(13), 2166-2168. https://doi.org/10.1097/QAD.0b013e328363b53f