Reactive hemophagocytosis in a patient with systemic lupus erythematosus and disseminated histoplasmosis

Shinpei Shibata, Deanna L. Kiska, Joseph B. Domachowske

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

We report a 16 year-old girl with systemic lupus erythematosus, treated with prednisone and mycophenolate, who developed fever of unknown origin. Her laboratory evaluation demonstrated reactive hemophagocytosis, the cause of which was ultimately determined to be disseminated infection with Histoplasma capsulatum. Treatment of the fungal infection led to rapid resolution of her hemophagocytic syndrome. This is the first reported case of histoplasmosis- induced hemophagocytic syndrome reported in an adolescent patient.

Original languageEnglish (US)
Pages (from-to)66-67
Number of pages2
JournalInfectious Diseases in Clinical Practice
Volume15
Issue number1
DOIs
StatePublished - Jan 2007
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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