Re-inventing adherence

Toward a patient-centered model of care for drug-resistant tuberculosis and HIV

M. R. O'Donnell, A. Daftary, M. Frick, Y. Hirsch-Moverman, K. R. Amico, M. Senthilingam, A. Wolf, J. Z. Metcalfe, P. Isaakidis, J. L. Davis, J. R. Zelnick, J. C M Brust, N. Naidu, M. Garretson, David Bangsberg, N. Padayatchi, G. Friedland

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

BACKGROUND: Despite renewed focus on molecular tuberculosis (TB) diagnostics and new antimycobacterial agents, treatment outcomes for patients co-infected with drug-resistant TB and human immunodeficiency virus (HIV) remain dismal, in part due to lack of focus on medication adherence as part of a patient-centered continuum of care. OBJECTIVE : To review current barriers to drug-resistant TB-HIV treatment and propose an alternative model to conventional approaches to treatment support. DISCUS S ION: Current national TB control programs rely heavily on directly observed therapy (DOT) as the centerpiece of treatment delivery and adherence support. Medication adherence and care for drug-resistant TBHIV could be improved by fully implementing teambased patient-centered care, empowering patients through counseling and support, maintaining a rightsbased approach while acknowledging the responsibility of health care systems in providing comprehensive care, and prioritizing critical research gaps. CONCLUS ION: It is time to re-invent our understanding of adherence in drug-resistant TB and HIV by focusing attention on the complex clinical, behavioral, social, and structural needs of affected patients and communities.

Original languageEnglish (US)
Pages (from-to)430-434
Number of pages5
JournalInternational Journal of Tuberculosis and Lung Disease
Volume20
Issue number4
DOIs
StatePublished - Apr 1 2016
Externally publishedYes

Fingerprint

Multidrug-Resistant Tuberculosis
Patient-Centered Care
Medication Adherence
HIV
Tuberculosis
Directly Observed Therapy
Continuity of Patient Care
Molecular Pathology
Critical Care
Counseling
Therapeutics
Anti-Bacterial Agents
Delivery of Health Care
Research
Pharmaceutical Preparations

Keywords

  • Drug-resistant TB
  • HIV
  • Medication adherence
  • Patient-centered care

ASJC Scopus subject areas

  • Medicine(all)
  • Pulmonary and Respiratory Medicine
  • Infectious Diseases

Cite this

O'Donnell, M. R., Daftary, A., Frick, M., Hirsch-Moverman, Y., Amico, K. R., Senthilingam, M., ... Friedland, G. (2016). Re-inventing adherence: Toward a patient-centered model of care for drug-resistant tuberculosis and HIV. International Journal of Tuberculosis and Lung Disease, 20(4), 430-434. https://doi.org/10.5588/ijtld.15.0360

Re-inventing adherence : Toward a patient-centered model of care for drug-resistant tuberculosis and HIV. / O'Donnell, M. R.; Daftary, A.; Frick, M.; Hirsch-Moverman, Y.; Amico, K. R.; Senthilingam, M.; Wolf, A.; Metcalfe, J. Z.; Isaakidis, P.; Davis, J. L.; Zelnick, J. R.; Brust, J. C M; Naidu, N.; Garretson, M.; Bangsberg, David; Padayatchi, N.; Friedland, G.

In: International Journal of Tuberculosis and Lung Disease, Vol. 20, No. 4, 01.04.2016, p. 430-434.

Research output: Contribution to journalArticle

O'Donnell, MR, Daftary, A, Frick, M, Hirsch-Moverman, Y, Amico, KR, Senthilingam, M, Wolf, A, Metcalfe, JZ, Isaakidis, P, Davis, JL, Zelnick, JR, Brust, JCM, Naidu, N, Garretson, M, Bangsberg, D, Padayatchi, N & Friedland, G 2016, 'Re-inventing adherence: Toward a patient-centered model of care for drug-resistant tuberculosis and HIV', International Journal of Tuberculosis and Lung Disease, vol. 20, no. 4, pp. 430-434. https://doi.org/10.5588/ijtld.15.0360
O'Donnell, M. R. ; Daftary, A. ; Frick, M. ; Hirsch-Moverman, Y. ; Amico, K. R. ; Senthilingam, M. ; Wolf, A. ; Metcalfe, J. Z. ; Isaakidis, P. ; Davis, J. L. ; Zelnick, J. R. ; Brust, J. C M ; Naidu, N. ; Garretson, M. ; Bangsberg, David ; Padayatchi, N. ; Friedland, G. / Re-inventing adherence : Toward a patient-centered model of care for drug-resistant tuberculosis and HIV. In: International Journal of Tuberculosis and Lung Disease. 2016 ; Vol. 20, No. 4. pp. 430-434.
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